ArticleGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2022
The correlation between pseudoexfoliation syndrome and the Triglyceride-Glucose index.
Article in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 10 citations in OpenAlex.
- Comparison of serum C3, C3a, C4 levels between cataract patients with and without pseudoexfoliation and normal individuals.BMC ophthalmology · 2026Article
- Evaluation of tear film function and ocular surface disease index in patients with unilateral pseudoexfoliation syndrome.International ophthalmology · 2025Article
- Systemic Immune-Inflammation Index and Unconjugated Bilirubin Levels Are Associated with Pseudoexfoliation Syndrome.Journal of ophthalmic & vision research · 2025Article
- Utility of the non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio in individuals with retinal vein occlusion.Frontiers in cardiovascular medicine · 2025Article
- Elevated triglyceride-glucose index increases risk in patients with retinal vein occlusion.Frontiers in medicine · 2025Article
- Could Triglyceride-Glucose Index, a Predictor of Atherosclerosis, Be Associated with Retinal Vein Occlusion?Turkish journal of ophthalmology · 2024Observational
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2 authors at 1 institution in 1 country.
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Abstract
purposePseudoexfoliation (PEX) syndrome is an age-related disease characterized by the accumulation of extracellular material in many ocular structures, skin and internal organs. Recent studies have shown that the Triglyceride-Glucose (TyG) index has clinical importance for the evaluation of vascular damage. The purpose of this study was to determine the relationship between PEX syndrome and TyG index, and to detect the risk in terms of vascular diseases.
methodsIn the present study, 50 patients with PEX syndrome who were admitted to the ophthalmology outpatient clinic were evaluated along with 50 others who made up the control group. The Triglyceride-Glucose index was calculated with fasting plasma glucose and triglyceride values.
resultsThe mean age was 68.2 ± 1.2 years and 61.0% of the patients were male. There was no statistically significant difference between the two groups in terms of blood sugar and lipid profile (except triglyceride) (p > 0.05). The TyG index value was 8.9 ± 0.5 in the PEX group and 8.6 ± 0.6 in the control group. This difference was statistically significant (p = 0.003). In univariate regression analysis, TyG index (OR = 2.81; CI: 1.37-5.75; p = 0.005) was found to be correlated with PEX. In multivariate logistic regression analysis, this correlation remained statistically significant when adjusted for age and sex (OR = 2.89; CI: 1.35-6.18; p = 0.006).
conclusionResults showed that the TyG index was high in patients diagnosed with PEX. The risk of vascular diseases can be determined by examining the TyG index in patients with PEX, and this predetermination would have significant consequences for public health.
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