Evidence map›Paper›PMID 35723765›Full record

ArticleSurgical case reports2022

Stage IV anal canal squamous cell carcinoma with long-term survival: a case report.

Katsuji Sawai, Takanori Goi, Noriyuki Tagai, Hidetaka Kurebayashi, Mitsuhiro Morikawa, Kenji Koneri, Masato Tamaki, Makoto Murakami, Yasuo Hirono, Hiroyuki Maeda

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Surgical case reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Factors Influencing Outcomes and Survival in Anal Cancer.Current oncology (Toronto, Ont.) · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Katsuji SawaiFirst Department of Surgery, University of Fukui, 23-3 Matsuoka Shimoaizuki Eiheiji-cho, Yoshidagun, Fukui, 910-1193, Japan. sawaika@hotmail.com.ORCID http://orcid.org/0000-0001-5170-4372
Takanori GoiFirst Department of Surgery, University of Fukui, 23-3 Matsuoka Shimoaizuki Eiheiji-cho, Yoshidagun, Fukui, 910-1193, Japan.
Noriyuki TagaiFirst Department of Surgery, University of Fukui, 23-3 Matsuoka Shimoaizuki Eiheiji-cho, Yoshidagun, Fukui, 910-1193, Japan.
Hidetaka KurebayashiFirst Department of Surgery, University of Fukui, 23-3 Matsuoka Shimoaizuki Eiheiji-cho, Yoshidagun, Fukui, 910-1193, Japan.
Mitsuhiro MorikawaFirst Department of Surgery, University of Fukui, 23-3 Matsuoka Shimoaizuki Eiheiji-cho, Yoshidagun, Fukui, 910-1193, Japan.
Kenji KoneriFirst Department of Surgery, University of Fukui, 23-3 Matsuoka Shimoaizuki Eiheiji-cho, Yoshidagun, Fukui, 910-1193, Japan.
Masato TamakiFirst Department of Surgery, University of Fukui, 23-3 Matsuoka Shimoaizuki Eiheiji-cho, Yoshidagun, Fukui, 910-1193, Japan.
Makoto MurakamiFirst Department of Surgery, University of Fukui, 23-3 Matsuoka Shimoaizuki Eiheiji-cho, Yoshidagun, Fukui, 910-1193, Japan.
Yasuo HironoCancer Care Promotion Center, Faculty of Medical Sciences, University of Fukui, 23-3 Matsuoka Shimoaizuki Eiheiji-cho, Yoshidagun, Fukui, 910-1193, Japan.
Hiroyuki MaedaFirst Department of Surgery, University of Fukui, 23-3 Matsuoka Shimoaizuki Eiheiji-cho, Yoshidagun, Fukui, 910-1193, Japan.
University of Fukui · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCurrently, no established standard treatment exists for metastatic anal squamous cell carcinoma. We report a case of complete response in a patient with stage IV anal squamous cell carcinoma after undergoing multidisciplinary treatment. CASE PRESENTATION: A 62-year-old woman visited a nearby doctor with a chief concern of severe pain associated with a firm mass in the anus. The patient was diagnosed with anal canal squamous cell carcinoma and liver metastases and referred to First Department of Surgery Faculty of Medicine University of Fukui for treatment. The patient received a TNM classification of T4N0M1 and stage IV. Rectal amputation was performed; however, postoperative complications hindered immediate anticancer therapy and the liver metastases exacerbated. Radiofrequency hyperthermia and systemic chemotherapy were performed 3 months postoperatively. A prominent reduction in the liver metastasis was observed. Lung metastases appeared during the course of systemic chemotherapy. Radiotherapy was performed to treat the lung lesion and resolved. Radiotherapy was also performed for liver metastasis. The lesion in the liver showed resolution after 54 months postoperatively, and treatment with the anticancer drug was discontinued. Ten-year follow-up findings suggested complete resolution of the lesion in response to the treatment protocol followed in this case. This long-term survival was achieved through a multidisciplinary treatment.

conclusionsThe present case suggests that multidisciplinary treatment approach is effective for resolving stage IV anal squamous cell carcinoma, and addition of new anticancer drug therapy may improve the overall prognosis of squamous cell carcinoma.

Indexed as

Anal squamous cell carcinomaLong-term survivalMultidisciplinary treatment

Identifiers

PMID35723765
PMCPMC9209564
OpenAlexW4283159460

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.