Evidence map›Paper›PMID 35723692›Full record

ReviewApplied microbiology and biotechnology2022

Natural products from Photorhabdus and Xenorhabdus: mechanisms and impacts.

Harun Cimen, Mustapha Touray, Sebnem Hazal Gulsen, Selcuk Hazir

Abstract readReview
PubMed Publisher
In one paragraph

Review in Applied microbiology and biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
10.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Genomic Insights and Antifungal Efficacy ofJournal of fungi (Basel, Switzerland) · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Fighting Antimicrobial Resistance: Innovative Drugs in Antibacterial Research.Angewandte Chemie (International ed. in English) · 2025
    Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. ExploringMolecules (Basel, Switzerland) · 2024
    Review
  13. Antagonistic Efficacy of Symbiotic BacteriumJournal of microbiology and biotechnology · 2024
    Article
  14. Review
  15. Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Harun CimenDepartment of Biology, Faculty of Arts and Sciences, Aydin Adnan Menderes University, Turkey, Aydin. haruncimenn@gmail.com.ORCID http://orcid.org/0000-0002-0106-4183
Mustapha TourayDepartment of Biology, Faculty of Arts and Sciences, Aydin Adnan Menderes University, Turkey, Aydin.ORCID http://orcid.org/0000-0002-9550-0782
Sebnem Hazal GulsenDepartment of Biology, Faculty of Arts and Sciences, Aydin Adnan Menderes University, Turkey, Aydin.ORCID http://orcid.org/0000-0001-6981-7025
Selcuk HazirDepartment of Biology, Faculty of Arts and Sciences, Aydin Adnan Menderes University, Turkey, Aydin.ORCID http://orcid.org/0000-0001-9298-1472
Adnan Menderes University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Insects and fungal pathogens pose constant problems to public health and agriculture, especially in resource-limited parts of the world; and the use of chemical pesticides continues to be the main methods for the control of these organisms. Photorhabdus spp. and Xenorhabdus spp., (Fam; Morganellaceae), enteric symbionts of Steinernema, and Heterorhabditis nematodes are naturally found in soil on all continents, except Antarctic, and on many islands throughout the world. These bacteria produce diverse secondary metabolites that have important biological and ecological functions. Secondary metabolites include non-ribosomal peptides, polyketides, and/or hybrid natural products that are synthesized using polyketide synthetase (PRS), non-ribosomal peptide synthetase (NRPS), or similar enzymes and are sources of new pesticide/drug compounds and/or can serve as lead molecules for the design and synthesize of new alternatives that could replace current ones. This review addresses the effects of these bacterial symbionts on insect pests, fungal phytopathogens, and animal pathogens and discusses the substances, mechanisms, and impacts on agriculture and public health. KEY POINTS: • Insects and fungi are a constant menace to agricultural and public health. • Chemical-based control results in resistance development. • Photorhabdus and Xenorhabdus are compelling sources of biopesticides.

Indexed as

Biological ProductsNematodaPhotorhabdusRhabditidaXenorhabdusAnimalsInsectaSymbiosisBiological ProductsBacterial secondary metabolitesEntomopathogenic nematodesPhotorhabdusXenorhabdus

Identifiers

PMID35723692
OpenAlexW4283168246

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.