Evidence map›Paper›PMID 35723380›Full record

ArticleCurrent issues in molecular biology2021

Structural and Functional Characterization of a Novel Recombinant Antimicrobial Peptide from

Angela Di Somma, Antonio Moretta, Carolina Cané, Carmen Scieuzo, Rosanna Salvia, Patrizia Falabella, Angela Duilio

Open access · goldAbstract read
In one paragraph

Article in Current issues in molecular biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
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  6. Review
  7. Article
  8. Peptide Fractions Extracted from the Hemolymph ofInternational journal of molecular sciences · 2025
    Article
  9. Biological Activity of Peptide Fraction Derived fromInternational journal of molecular sciences · 2025
    Article
  10. Article
  11. Article
  12. Article
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  14. Article
  15. Article
  16. Article
  17. Insects · 2023
    Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Angela Di SommaDepartment of Chemical Sciences, University of Naples "Federico II", Via Cinthia 4, 80126 Napoli, Italy.ORCID 0000-0003-4916-7875
Antonio MorettaDepartment of Sciences, University of Basilicata, 85100 Potenza, Italy.
Carolina CanéDepartment of Chemical Sciences, University of Naples "Federico II", Via Cinthia 4, 80126 Napoli, Italy.
Carmen ScieuzoDepartment of Sciences, University of Basilicata, 85100 Potenza, Italy.
Rosanna SalviaDepartment of Sciences, University of Basilicata, 85100 Potenza, Italy.ORCID 0000-0002-6661-7164
Patrizia FalabellaDepartment of Sciences, University of Basilicata, 85100 Potenza, Italy.ORCID 0000-0003-0304-6867
Angela DuilioDepartment of Chemical Sciences, University of Naples "Federico II", Via Cinthia 4, 80126 Napoli, Italy.
University of Basilicata · ITCeinge Biotecnologie Avanzate (Italy) · ITIstituto Nazionale Biostrutture e Biosistemi · ITUniversity of Naples Federico II · IT

Funding

Ministry of Education, Universities and Research ARS01_00597PRIN 2017 "Identification and characterization of novel antitumoral/antimicrobial insect-derived peptides: a multidisciplinary, integrated approach from in silico to in vivo"
6 · The paper itself

Abstract

Antibiotics are commonly used to treat pathogenic bacteria, but their prolonged use contributes to the development and spread of drug-resistant microorganisms raising the challenge to find new alternative drugs. Antimicrobial peptides (AMPs) are small/medium molecules ranging 10-60 residues synthesized by all living organisms and playing important roles in the defense systems. These features, together with the inability of microorganisms to develop resistance against the majority of AMPs, suggest that these molecules might represent effective alternatives to classical antibiotics. Because of their high biodiversity, with over one million described species, and their ability to live in hostile environments, insects represent the largest source of these molecules. However, production of insect AMPs in native forms is challenging. In this work we investigate a defensin-like antimicrobial peptide identified in the

Indexed as

antibacterial activityantimicrobial peptidesdefensinsHermetia illucensinsects

Identifiers

PMID35723380
PMCPMC8929087
OpenAlexW4200530202

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.