Evidence map›Paper›PMID 35723379›Full record

ArticleCurrent issues in molecular biology2022

Dysregulation of miR-21-5p, miR-93-5p, miR-200c-3p and miR-205-5p in Oral Squamous Cell Carcinoma: A Potential Biomarkers Panel?

Ovidiu Aghiorghiesei, Oana Zanoaga, Lajos Raduly, Alexandra Iulia Aghiorghiesei, Paul Chiroi, Andrada Trif, Rares Buiga, Liviuta Budisan, Ondine Lucaciu, Laura Ancuta Pop and 3 more

Open access · goldAbstract read
In one paragraph

Article in Current issues in molecular biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. Article
  8. Review
  9. CaCOJournal of dental research · 2024
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. miR-125b-5p, miR-155-3p, and miR-214-5p and TargetInternational journal of molecular sciences · 2023
    Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Ovidiu AghiorghieseiDepartment of Oral Health, "Iuliu Haţieganu" University of Medicine and Pharmacy, 15 Victor Babeș Street, 400012 Cluj-Napoca, Cluj, Romania.
Oana ZanoagaResearch Center for Functional Genomics, Biomedicine and Translational Medicine, "Iuliu Haţieganu" University of Medicine and Pharmacy, 15 Victor Babeș Street, 400012 Cluj-Napoca, Cluj, Romania.
Lajos RadulyResearch Center for Functional Genomics, Biomedicine and Translational Medicine, "Iuliu Haţieganu" University of Medicine and Pharmacy, 15 Victor Babeș Street, 400012 Cluj-Napoca, Cluj, Romania.ORCID 0000-0002-3926-5423
Alexandra Iulia AghiorghieseiDepartment of Prosthetics and Dental Materials, "Iuliu Haţieganu" University of Medicine and Pharmacy, 15 Victor Babeș Street, 400012 Cluj-Napoca, Cluj, Romania.
Paul ChiroiResearch Center for Functional Genomics, Biomedicine and Translational Medicine, "Iuliu Haţieganu" University of Medicine and Pharmacy, 15 Victor Babeș Street, 400012 Cluj-Napoca, Cluj, Romania.ORCID 0000-0002-7019-1426
Andrada TrifEmergency County Hospital, 3-5 Clinicilor Street, 400000 Cluj-Napoca, Cluj, Romania.
Rares BuigaDepartment of Pathology, The Oncology Institute "Prof. Dr. Ion Chiricuta", 34-36 Republicii Street, 400015 Cluj-Napoca, Cluj, Romania.
Liviuta BudisanResearch Center for Functional Genomics, Biomedicine and Translational Medicine, "Iuliu Haţieganu" University of Medicine and Pharmacy, 15 Victor Babeș Street, 400012 Cluj-Napoca, Cluj, Romania.ORCID 0000-0001-5725-662X
Ondine LucaciuDepartment of Oral Health, "Iuliu Haţieganu" University of Medicine and Pharmacy, 15 Victor Babeș Street, 400012 Cluj-Napoca, Cluj, Romania.
Laura Ancuta PopResearch Center for Functional Genomics, Biomedicine and Translational Medicine, "Iuliu Haţieganu" University of Medicine and Pharmacy, 15 Victor Babeș Street, 400012 Cluj-Napoca, Cluj, Romania.ORCID 0000-0002-5806-0220
Cornelia BraicuResearch Center for Functional Genomics, Biomedicine and Translational Medicine, "Iuliu Haţieganu" University of Medicine and Pharmacy, 15 Victor Babeș Street, 400012 Cluj-Napoca, Cluj, Romania.ORCID 0000-0002-3055-4747
Radu CampianDepartment of Oral Rehabilitation, "Iuliu Haţieganu" University of Medicine and Pharmacy, 15 Victor Babeș Street, 400012 Cluj-Napoca, Cluj, Romania.
Ioana Berindan-NeagoeResearch Center for Functional Genomics, Biomedicine and Translational Medicine, "Iuliu Haţieganu" University of Medicine and Pharmacy, 15 Victor Babeș Street, 400012 Cluj-Napoca, Cluj, Romania.ORCID 0000-0001-5828-1325
Iuliu Hațieganu University of Medicine and Pharmacy · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oral squamous cell carcinoma (OSCC) is considered the sixth most common cancer worldwide. To reduce the high mortality of the disease, sensitive and specific diagnostic and prognostic biomarkers are urgently needed. Non-coding RNA, microRNAs (miRNAs), which are short length non-coding transcripts, or long non-coding RNA (lncRNA) seem to be potential biomarkers, considering that they have an important role in regulation of cell fate being involved in a wide range of biological processes. Literature data emphasized the important role of these transcripts as a biomarker for diagnosis and prognosis in oral squamous cell carcinoma. Therefore, we have evaluated the expression levels of a panel of four miRNAs (

Indexed as

immunohistochemistrymiRNAs and lncRNA profilingoral cancersquamous cell carcinoma

Identifiers

PMID35723379
PMCPMC9164081
OpenAlexW4224050056

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.