Evidence map›Paper›PMID 35723334›Full record

ReviewCurrent issues in molecular biology2022

Evidence from a Systematic Review and Meta-Analysis Pointing to the Antidiabetic Effect of Polyphenol-Rich Plant Extracts from

Michal Krawczyk, Izabela Burzynska-Pedziwiatr, Lucyna Alicja Wozniak, Malgorzata Bukowiecka-Matusiak

Open access · goldAbstract readReview
In one paragraph

Review in Current issues in molecular biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
4.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Effect ofFrontiers in pharmacology · 2025
    Pooled it
  2. Trial
  3. Review
  4. Article
  5. Hypoglycemic Assessment of Aqueous Leaf Extract ofBiochemistry research international · 2024
    Article
  6. Effects ofJournal of nutrition and metabolism · 2024
    Review
  7. Efficacy of Hot Tea Infusion vs. Ethanolic Extract ofJournal of nutrition and metabolism · 2024
    Article
  8. Article
  9. Article
  10. Bioactives ofMolecules (Basel, Switzerland) · 2022
    Review
  11. Antidiabetic Activity ofAvicenna journal of medical biotechnology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Michal KrawczykChair of Medical Biology, Laboratory of Metabolomic Studies, Department of Structural Biology, Faculty of Medicine, Faculty of Biomedical Sciences, Medical University of Lodz, Zeligowskiego 7/9, 90-752 Lodz, Poland.
Izabela Burzynska-PedziwiatrChair of Medical Biology, Laboratory of Metabolomic Studies, Department of Structural Biology, Faculty of Medicine, Faculty of Biomedical Sciences, Medical University of Lodz, Zeligowskiego 7/9, 90-752 Lodz, Poland.ORCID 0000-0002-3629-0981
Lucyna Alicja WozniakChair of Medical Biology, Laboratory of Metabolomic Studies, Department of Structural Biology, Faculty of Medicine, Faculty of Biomedical Sciences, Medical University of Lodz, Zeligowskiego 7/9, 90-752 Lodz, Poland.ORCID 0000-0002-9966-1807
Malgorzata Bukowiecka-MatusiakChair of Medical Biology, Laboratory of Metabolomic Studies, Department of Structural Biology, Faculty of Medicine, Faculty of Biomedical Sciences, Medical University of Lodz, Zeligowskiego 7/9, 90-752 Lodz, Poland.ORCID 0000-0002-6021-5711
Medical University of Lodz · PL

Funding

Medical University of Lodz 502-03/0-160-01/502-04-034 to Michal Krawczyk
6 · The paper itself

Abstract

In vitro and animal model studies are of great interest for selecting new phytochemicals, including polyphenols with antioxidative properties, as candidates for antidiabetic drugs. This review provides evidence from a critical literature data analysis on the effects of plant extract supplementation in diabetes mellitus management. We considered and meta-analyzed the efficacy of oral supplementation of plant extracts in animal model studies and examined physiological and oxidative stress parameters. Finally, 23 articles were included in the meta-analysis, revealing three plants with experimentally confirmed in vivo and in vitro antidiabetic properties:

Indexed as

diabetic ratsoxidative stressphytochemicalsplant extractssupplementation

Identifiers

PMID35723334
PMCPMC8928996
OpenAlexW4210456813

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.