Evidence map›Paper›PMID 35723308›Full record

ArticleCurrent issues in molecular biology2022

Repeated Home-Applied Dual-Light Antibacterial Photodynamic Therapy Can Reduce Plaque Burden, Inflammation, and aMMP-8 in Peri-Implant Disease-A Pilot Study.

Hanna Lähteenmäki, Tommi Pätilä, Ismo T Räisänen, Esko Kankuri, Taina Tervahartiala, Timo Sorsa

8 registry-linked trialsOpen access · goldAbstract read
In one paragraph

Article in Current issues in molecular biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 8 registered trials, which are not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05720104 nawithdrawnnot on this mapstarted 2023, after this paper: background citation

Effect of Regular Antibacterial Photodynamic Therapy on Oral Hygiene in the Elderly 24-hour Care Residents

TypeinterventionalSponsorKoite Health OyRan2023 to 2026Enrolled0ConditionsInflamed Gums, Dryness Oral, PlaqueArmsLumoral Treatment, Standard oral hygiene instructions
NCT05853679 nacompletednot on this map

Effect of Regular Antibacterial Photodynamic Therapy on Oral Hygiene in Elderly Residents of a 24-hour Care Facility

TypeinterventionalSponsorKoite Health OyRan2022 to 2023Enrolled31ConditionsDental Plaque, Pus Collection, Oral Disease, Dryness OralArmsLumoral Treatment, Standard oral hygiene instructions according to the Finnish Dental Association
NCT05962801 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Regular Home Use of Dual-light Photodynamic Therapy as an Adjunct to Non-surgical Periodontal Treatment in Smokers

TypeinterventionalSponsorAristotle University Of ThessalonikiRan2023 to 2024Enrolled60ConditionsPeriodontitis, Dual- Light Photodynamic Therapy, Smoking, Cigarette, Non-surgical Periodontal TherapyArmsLumoral device, Lumorinse
NCT06017817 narecruitingnot on this mapstarted 2024, after this paper: background citation

Regular Home-use of Antibacterial Photodynamic Therapy in the Management of Peri-implantitis

TypeinterventionalSponsorKoite Health OyRan2024 to 2026Enrolled80ConditionsPeri-Implantitis, Plaque, DentalArmsLumoral Treatment, Standard oral hygiene instructions, Scaling and root planing (SRP, surgical anti-infective peri-implantitis treatment
NCT06576063 narecruitingnot on this mapstarted 2025, after this paper: background citation

Effects of the Regular Use of Antibacterial Photodynamic Therapy as an Adjunctive Treatment on Oral Hygiene in Elderly Persons Living at Home or at Care Homes

TypeinterventionalSponsorKoite Health OyRan2025 to 2027Enrolled100ConditionsDental Plaque, Bleeding of Subgingival Space, Oral ComplicationArmsLumoral Treatment, Standard oral hygiene methods
NCT06859866 narecruitingnot on this mapstarted 2025, after this paper: background citation

Efficacy of Adjunctive At-Home Photodynamic Therapy (aPDT) in the Treatment of Peri-Implant Mucositis: A Post-Marketing Interventional Pilot Study With a Medical Device

TypeinterventionalSponsorKoite Health OyRan2025 to 2027Enrolled30ConditionsPeri-implant MucositisArmsStandard oral hygiene, The addition of home-based dual-light photodynamic therapy (Lumorinse® + Lumoral®)
NCT06860321 nacompletednot on this mapstarted 2025, after this paper: background citation

Photodynamic Treatment in the Management of Residual Biofilm - a Crossover Study

TypeinterventionalSponsorKoite Health OyRan2025 to 2025Enrolled20ConditionsHealthy Adults, Plaque, DentalArmsAdjunct antibacterial home-use dual-light medical device, Regular oral self care
NCT06877546 naactive not recruitingnot on this mapstarted 2025, after this paper: background citation

Photodynamic Treatment as Part of Oral Healthcare on Persons With Sjögren's Syndrome

TypeinterventionalSponsorKoite Health OyRan2025 to 2025Enrolled16ConditionsSjogren Syndrome, XerostomiaArmsLumoral treatment
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

  1. Trial
  2. Peri-Implant Diseases: Enhanced Antibacterial Photodynamic Therapy.Clinical and experimental dental research · 2025
    Trial
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Periodontal Disease - A Late Complication of Head and Neck Cancer Radiotherapy.Cancer control : journal of the Moffitt Cancer Center
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 2 countries.

Hanna LähteenmäkiDepartment of Oral and Maxillofacial Diseases, University of Helsinki and Helsinki University Hospital, 00280 Helsinki, Finland.ORCID 0000-0002-7914-9726
Tommi PätiläDepartment of Pediatric Heart Surgery and Organ Transplantation, New Children's Hospital, Helsinki University, 00100 Helsinki, Finland.
Ismo T RäisänenDepartment of Oral and Maxillofacial Diseases, University of Helsinki and Helsinki University Hospital, 00280 Helsinki, Finland.ORCID 0000-0001-5821-5299
Esko KankuriDepartment of Pharmacology, Helsinki University, 00100 Helsinki, Finland.ORCID 0000-0002-2193-8773
Taina TervahartialaDepartment of Oral and Maxillofacial Diseases, University of Helsinki and Helsinki University Hospital, 00280 Helsinki, Finland.ORCID 0000-0001-8817-896X
Timo SorsaDepartment of Oral and Maxillofacial Diseases, University of Helsinki and Helsinki University Hospital, 00280 Helsinki, Finland.
University of Helsinki · FI

Funding

Finnish Dental Society Apollonia 4000
6 · The paper itself

Abstract

Until now, in clinical dentistry, antibacterial photodynamic therapy (aPDT) has been restricted to in-office treatments, which hampers repeated applications. This pilot study tested the benefit of a commercially available Lumoral

Indexed as

aMMP-8antibacterial photodynamic therapyoral hygieneperi-implant disease

Identifiers

PMID35723308
PMCPMC8947626
OpenAlexW4220873424

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

and 2 more above

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.