Evidence map›Paper›PMID 35723071›Full record

ArticleJournal of orthodontics2022

The effect of maternal smoking and alcohol consumption on lip morphology.

Kristian James Michael Davies, Stephen Richmond, Renata Jorge Medeiros-Mirra, Hawraa Hassan Abbas, Caryl Eleri Wilson-Nagrani, Megan Gael Davis, Alexei Zhurov

Abstract read
In one paragraph

Article in Journal of orthodontics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kristian James Michael DaviesDepartment of Orthodontics, School of Dentistry, Cardiff University, Cardiff, UK.ORCID 0000-0001-8780-3735
Stephen RichmondDepartment of Orthodontics, School of Dentistry, Cardiff University, Cardiff, UK.
Renata Jorge Medeiros-MirraDepartment of Orthodontics, School of Dentistry, Cardiff University, Cardiff, UK.
Hawraa Hassan AbbasDepartment of Orthodontics, School of Dentistry, Cardiff University, Cardiff, UK.
Caryl Eleri Wilson-NagraniDepartment of Orthodontics, School of Dentistry, Cardiff University, Cardiff, UK.
Megan Gael DavisDepartment of Orthodontics, School of Dentistry, Cardiff University, Cardiff, UK.
Alexei ZhurovDepartment of Orthodontics, School of Dentistry, Cardiff University, Cardiff, UK.

Funding

Medical Research Council G9815508Medical Research Council MC_PC_15018Medical Research Council MC_PC_19009Wellcome Trust
6 · The paper itself

Abstract

objectiveTo determine whether maternal smoking and/or alcohol consumption has an influence on lip morphology. Maternal smoking is a known risk factor for orofacial clefts; however, its influence on normal lip variation is unknown. Recent research regarding normal lip morphology has been contradictory.

designRetrospective cohort study. SETTING AND

participantsA total of 4747 children from the Avon Longitudinal Study of Parents and Children (ALSPAC) who each had 3D facial scans carried out at 15 years of age were included in the study.

methodsEach of the participants was automatically categorised regarding predetermined lip morphological traits. Questionnaires completed by their mothers identified smoking and alcohol habits during pregnancy. Logistic regression analyses were applied to determine the effect of maternal smoking and alcohol consumption on lip morphology.

resultsMaternal smoking has significant effects on upper and lower lip contours, Cupid's bow, lower lip-chin shape and lower lip tone (all

conclusionMaternal smoking influences a number of lip traits, including a possible epigenetic effect on upper lip contour. Maternal alcohol consumption, particularly at a high level, influences philtrum shape. Maternal smoking and alcohol consumption have a combined effect on lower lip contour and lower lip-chin shape.

Indexed as

Cleft LipCleft PalateAlcohol DrinkingChildEthanolFemaleHumansLongitudinal StudiesPregnancyRetrospective StudiesSmokingEthanol3D imagingALSPACfacial morphologyfacial shapeimaging and cephalometrylip morphologylip shapematernal alcoholmaternal smoking

Identifiers

PMID35723071
PMCPMC9679570

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.