ArticleHuman reproduction open2022
Diagnosing chronic endometritis: when simplification fails to clarify.
Article in Human reproduction open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.
- Chronic Endometritis and Endometriosis: Two Sides of the Same Coin?Reproductive sciences (Thousand Oaks, Calif.) · 2025Pooled it
- An endometrial immune atlas across the female menstrual cycle reveals lymphoid aggregates compromise pregnancy.Nature communications · 2026Article
- Pyroptosis in endometritis: Molecular mechanisms, pathogenic roles, and therapeutic opportunities.iScience · 2026Review
- The Role of Endometrial Microbiota in the Pathogenesis of Chronic Endometritis: A Systematic Review and Meta-Analysis.Biomedicines · 2026Review
- Multidimensional regulatory architecture of endometrial receptivity and its translational implications for implantation failure.Frontiers in endocrinology · 2026Review
- Therapeutic potential and mechanisms of plant metabolites in endometritis: a comprehensive review.Frontiers in pharmacology · 2026Review
- Empirical Antibiotic Therapy in Chronic Endometritis With and Without Focal Lesions: A Prospective Cohort Study.Medical sciences (Basel, Switzerland) · 2025Article
- Implantation Failure: Where to Look Up?Journal of clinical medicine · 2025Review
- CD56-Positive NK Cells and CD138-Positive Plasma Cells in Basal Decidua of Term Placentas in Singleton Pregnancies After Assisted Reproductive Technology Treatment of Endometriosis-Related Infertility.Life (Basel, Switzerland) · 2025Article
- Evaluation of Lipopolysaccharide and Interleukin-6 as Useful Screening Tool for Chronic Endometritis.International journal of molecular sciences · 2024Article
- Investigating bacteria-induced inflammatory responses using novel endometrial epithelial gland organoid models.Frontiers in reproductive health · 2024Article
- Hysteroscopic versus histopathological agreement in the diagnosis of chronic endometritis: results from a retrospective observational study.Archives of gynecology and obstetrics · 2023Observational
- The Role of Plasma Cells as a Marker of Chronic Endometritis: A Systematic Review and Meta-Analysis.Biomedicines · 2023Review
- LPS Administration during Fertilization Affects Epigenetic Inheritance during Embryonic Development.Animals : an open access journal from MDPI · 2023Article
- Successful Live Birth Following Treatment of Persistent Endometrial Dysbiosis and Recurrent Chronic Endometritis: A Case Report.Reproductive medicine and biologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Reproductive immunology has grown in importance in recent years and has even developed into a discipline of its own within the field of reproductive medicine. Many aspects of reproductive failure such as repeated implantation failure or recurrent miscarriages are, meanwhile, seen as a consequence of aberrant expression of immunological factors. This is reflected by the increasing number of tests for assessing and quantifying different immune cell types as well as by a wide range of immune therapies offered to a clientele consisting of desperate patients requesting additional 'IVF tools': first, what is still usually disregarded is the enormous plasticity and fluctuation of most immune cells in the genital tract; second, their still poorly characterized functions in the endometrial cycle: further, their partially unknown role in embryo implantation and in establishing a pregnancy; and third, the fact that one of the fundamental hypotheses of reproductive immunology-of note-the Medawar concept or 'Medawar's Paradox' of semi-allogeneic graft embryo, is partially based on an erroneous assumption, i.e. the immunologic rejection and tolerance of an embryo. In the present opinion article, we comment on the diagnostic procedures and therapy approaches for chronic endometritis within the scope of reproductive medicine.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.