Evidence map›Paper›PMID 35722129›Full record

ArticleFrontiers in cardiovascular medicine2022

QTc Dynamics Following Cardioversion for Persistent Atrial Fibrillation.

Arwa Younis, Nofrat Nehoray, Michael Glikson, Christopher Bodurian, Eyal Nof, Nicola Luigi Bragazzi, Michael Berger, Wojciech Zareba, Ilan Goldenberg, Roy Beinart

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cardiovascular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 3 countries.

Arwa YounisCardiac Electrophysiology and Pacing Section, Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, OH, United States.
Nofrat NehorayChaim Sheba Medical Center Affiliated to Sackler Medical School, Tel Aviv University, Ramat Gan, Israel.
Michael GliksonHeart Center, Shaare Zedek Medical Center, Jerusalem, Israel.
Christopher BodurianClinical Cardiovascular Research Center, University of Rochester, Rochester, NY, United States.
Eyal NofChaim Sheba Medical Center Affiliated to Sackler Medical School, Tel Aviv University, Ramat Gan, Israel.
Nicola Luigi BragazziLaboratory for Industrial and Applied Mathematics, Center for Disease Modeling, York University, Toronto, ON, Canada.
Michael BergerChaim Sheba Medical Center Affiliated to Sackler Medical School, Tel Aviv University, Ramat Gan, Israel.
Wojciech ZarebaClinical Cardiovascular Research Center, University of Rochester, Rochester, NY, United States.
Ilan GoldenbergClinical Cardiovascular Research Center, University of Rochester, Rochester, NY, United States.
Roy BeinartChaim Sheba Medical Center Affiliated to Sackler Medical School, Tel Aviv University, Ramat Gan, Israel.
Tel Aviv University · ILUniversity of Rochester · USCleveland Clinic · USShaare Zedek Medical Center · ILSheba Medical Center · ILYork University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Cardioversion (CV) for atrial fibrillation (AF) is common. We aimed to assess changes in QTc over time following electrical CV (ECV) for persistent AF, and to compare the benefit of using continuous Holter monitoring vs. conventional follow-up by ECG. Methods: Prospective observational cohort study. We comprised 90 patients admitted to our center for elective ECV due to persistent AF who were prospectively enrolled from July 2017 to August 2018. All patients underwent 7-days Holter started prior to ECV. Baseline QTc was defined as median QTc during 1 h post ECV. The primary endpoint was QTc prolongation defined as QTc ≥500 ms, or ≥10% increase (if baseline QTc was >480 ms). Conventional monitoring was defined as 2-h ECG post ECV. Results: Mean age was 67 ± 11 years and 61% were male. Median baseline QTc was 452 ms (IQ range: 431-479 ms) as compared with a maximal median QTc of 474 ms (IQ range: 433-527 ms; Conclusions: ECV of patients with persistent AF was associated with increased transient risk of QTc prolongation in nearly half of the patients. Peak median QTc occurs during end of second day following ECV and prolonged ECG monitoring provides superior detection of significant QTc prolongation compared with conventional monitoring.

Indexed as

cardioversionpersistent atrial fibrillationQTc prolongationQT intervalsafety

Identifiers

PMID35722129
PMCPMC9205203
OpenAlexW4281790742

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.