Evidence map›Paper›PMID 35722086›Full record

ArticleFrontiers in cardiovascular medicine2022

Case Report: Multimodal Imaging Guides the Management of an Eosinophilic Leukemia Patient With Eosinophilic Myocarditis and Intracardiac Thrombus.

Jinping Si, Xinxin Zhang, Na Chen, Fangfang Sun, Ping Du, Zhiyong Li, Di Tian, Xiuli Sun, Guozhen Sun, Tao Cong and 2 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in Frontiers in cardiovascular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Multimodality Imaging in Eosinophilic Myocarditis: A Rare Cause of Heart Failure.Journal of cardiovascular development and disease · 2025
    Review
  2. Article
  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Jinping SiDepartment of Cardiology, First Affiliated Hospital of Dalian Medical University, Dalian, China.
Xinxin ZhangDepartment of Cardiology, First Affiliated Hospital of Dalian Medical University, Dalian, China.
Na ChenDepartment of Cardiology, First Affiliated Hospital of Dalian Medical University, Dalian, China.
Fangfang SunDepartment of Nuclear Medicine, First Affiliated Hospital of Dalian Medical University, Dalian, China.
Ping DuDepartment of Cardiology, First Affiliated Hospital of Dalian Medical University, Dalian, China.
Zhiyong LiDepartment of Radiology, First Affiliated Hospital of Dalian Medical University, Dalian, China.
Di TianDepartment of Radiology, First Affiliated Hospital of Dalian Medical University, Dalian, China.
Xiuli SunDepartment of Hematology, First Affiliated Hospital of Dalian Medical University, Dalian, China.
Guozhen SunDepartment of Hematology, First Affiliated Hospital of Dalian Medical University, Dalian, China.
Tao CongDepartment of Ultrasonography, First Affiliated Hospital of Dalian Medical University, Dalian, China.
Xuemei DuDepartment of Nuclear Medicine, First Affiliated Hospital of Dalian Medical University, Dalian, China.
Ying LiuDepartment of Cardiology, First Affiliated Hospital of Dalian Medical University, Dalian, China.
First Affiliated Hospital of Dalian Medical University · CNDalian Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Eosinophilic leukemia (EL) is a rare, serious and potentially life-threatening condition characterized by the overproduction of eosinophils leading to tissue eosinophilic infiltration and damage. Although multiple organ systems may be involved, progressive eosinophilic myocarditis (EM) is the most common cause of morbidity and mortality. Early diagnosis and follow-up surveillance combined with multimodal imaging are crucial for appropriate treatment of EM. Case Summary: It's a rare case of EL with EM and intracardiac thrombus in a 59-year-old patient who presented with asthenia for 3 weeks. Full blood count analysis indicated significant eosinophilia. Bone marrow aspirate revealed dysplastic eosinophilia and a FIP1L1-PDGFRA fusion gene (4q12) was detected, confirming EL. Echocardiography revealed EM with intracardiac thrombus. This was later confirmed by cardiac magnetic resonance imaging. The patient was commenced on imatinib and prednisolone and good clinical response was obtained. Through 18F-FAPI PET/CT imaging, we obtained Conclusion: This case demonstrates

Indexed as

18F-FAPIeosinophilic leukemiafibroblast activation proteinPET/CTthrombotic

Identifiers

PMID35722086
PMCPMC9204136
OpenAlexW4281670400

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.