Evidence map›Paper›PMID 35721781›Full record

ArticleNature physics2021

Surface-tension-induced budding drives alveologenesis in human mammary gland organoids.

Pablo A Fernández, Benedikt Buchmann, Andriy Goychuk, Lisa K Engelbrecht, Marion K Raich, Christina H Scheel, Erwin Frey, Andreas R Bausch

Open access · greenAbstract read
In one paragraph

Article in Nature physics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 51 citations in OpenAlex.

  1. Review
  2. Article
  3. Single-cell chiral symmetry breaking under confinement.bioRxiv : the preprint server for biology · 2026
    Article
  4. Review
  5. Article
  6. Collective migration modes in development, tissue repair and cancer.Nature reviews. Molecular cell biology · 2025
    Review
  7. Article
  8. Article
  9. Generalized Spin-Curl Force Beyond the Stress Tensor.Sensors (Basel, Switzerland) · 2025
    Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Review
  15. Article
  16. Primary human organoids models: Current progress and key milestones.Frontiers in bioengineering and biotechnology · 2023
    Review
  17. Biomimetic Gland Models with Engineered Stratagems.Research (Washington, D.C.) · 2023
    Review
  18. Article
  19. Article
  20. Mechanical coupling of supracellular stress amplification and tissue fluidization during exit from quiescence.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Pablo A Fernández *Center for Protein Assemblies and Lehrstuhl für Biophysik (E27), Physics Department, Technische Universität München, Garching, Germany.
Benedikt Buchmann *Center for Protein Assemblies and Lehrstuhl für Biophysik (E27), Physics Department, Technische Universität München, Garching, Germany.
Andriy Goychuk *Arnold Sommerfeld Center for Theoretical Physics and Center for NanoScience, Ludwig-Maximilians-Universität München, Munich, Germany.ORCID https://orcid.org/0000-0001-6776-9437
Lisa K EngelbrechtCenter for Protein Assemblies and Lehrstuhl für Biophysik (E27), Physics Department, Technische Universität München, Garching, Germany.
Marion K RaichCenter for Protein Assemblies and Lehrstuhl für Biophysik (E27), Physics Department, Technische Universität München, Garching, Germany.
Christina H ScheelInstitute of Stem Cell Research, Helmholtz Center for Health and Environmental Research Munich, Neuherberg, Germany.
Erwin FreyArnold Sommerfeld Center for Theoretical Physics and Center for NanoScience, Ludwig-Maximilians-Universität München, Munich, Germany.ORCID https://orcid.org/0000-0001-8792-3358
Andreas R BauschCenter for Protein Assemblies and Lehrstuhl für Biophysik (E27), Physics Department, Technische Universität München, Garching, Germany.ORCID https://orcid.org/0000-0002-4608-9544
Technical University of Munich · DECenter for NanoScience · DEHelmholtz Zentrum München · DE

Funding

European Research Council 810104
6 · The paper itself

Abstract

Organ development involves complex shape transformations driven by active mechanical stresses that sculpt the growing tissue

Identifiers

PMID35721781
PMCPMC7612858
OpenAlexW3201875431

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.