Evidence map›Paper›PMID 35721764›Full record

ArticleFrontiers in endocrinology2022

Associations Between Body Composition, Leptin, and Vitamin D Varied by the Body Fat Percentage in Adolescents.

Rapheeporn Khwanchuea, Chuchard Punsawad

Open access · goldAbstract read
In one paragraph

Article in Frontiers in endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 18 citations in OpenAlex.

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  8. Nutrients · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Rapheeporn KhwanchueaSchool of Medicine, Walailak University, Nakhonsithammarat, Thailand.
Chuchard PunsawadSchool of Medicine, Walailak University, Nakhonsithammarat, Thailand.
Walailak University · TH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Serum leptin levels reflects one's degree of obesity and can affect vitamin D levels. The relationship between body fat, leptin, and 25-hydroxyvitamin D (25(OH)D) has not been extensively studied in adolescents. This study aimed to investigate the correlations between body composition and leptin and 25(OH)D levels in boys and girls. Methods: Participants aged 12-14 years (n = 205) were grouped according to sex. After body composition was recorded using bioelectrical impedance analysis, they were classified into three groups according to body fat percentage (%BF) (< 30, ≥ 30 and < 40, and ≥ 40). Serum leptin and 25(OH)D levels were measured using the enzyme-linked immunosorbent assay (ELISA). Correlations between all variables were analyzed according to sex and the percentage of BF groups. Results: Boys and girls with %BF ≥ 30 showed no difference in body mass index (BMI), %BF, and leptin and 25(OH)D, while other variables of body composition were more common in boys than in girls. The %BF, body fat mass (BFM), and 25(OH)D of both sexes with %BF ≥ 30, and leptin levels of boys with %BF ≥ 40 increased with an increase in %BF. A negative correlation between leptin and 25(OH)D levels was found in boys with %BF < 40 and girls with %BF < 30. In the %BF ≥ 30 and < 40 groups, there were negative correlations between leptin, BFM, free fat mass, and muscle mass (MM); between leptin, 25(OH)D, and height in boys; and between 25(OH)D, body weight, BMI, and MM in girls. Conclusion: A negative correlation between leptin and 25(OH)D levels varied according to sex, while for body composition, it was evident at 30 and 40% BF.

Indexed as

Body CompositionLeptinAdipose TissueAdolescentBody Mass IndexFemaleHumansMaleVitamin DVitaminsLeptinVitamin DVitamins25-hydroxyvitamin Dadolescentsbody compositionbody fat percentage (BF%)leptin

Identifiers

PMID35721764
PMCPMC9203737
OpenAlexW4281802546

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.