Evidence map›Paper›PMID 35721762›Full record

ArticleFrontiers in endocrinology2022

The Lower Limit of Reference of Urinary Albumin/Creatinine Ratio and the Risk of Chronic Kidney Disease Progression in Patients With Type 2 Diabetes Mellitus.

Wei-Hua Tang, Wei-Chin Hung, Chao-Ping Wang, Cheng-Ching Wu, Chin-Feng Hsuan, Teng-Hung Yu, Chia-Chang Hsu, Ya-Ai Cheng, Fu-Mei Chung, Yau-Jiunn Lee and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 20 citations in OpenAlex.

  1. Observational
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  7. Association ofDiagnostics (Basel, Switzerland) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Wei-Hua TangDivision of Cardiology, Department of Internal Medicine, Taipei Veterans General Hospital, Yuli Branch, Hualien, Taiwan.
Wei-Chin HungDivision of Cardiology, Department of Internal Medicine, E-Da Hospital, Kaohsiung, Taiwan.
Chao-Ping WangDivision of Cardiology, Department of Internal Medicine, E-Da Hospital, Kaohsiung, Taiwan.
Cheng-Ching WuDivision of Cardiology, Department of Internal Medicine, E-Da Hospital, Kaohsiung, Taiwan.
Chin-Feng HsuanDivision of Cardiology, Department of Internal Medicine, E-Da Hospital, Kaohsiung, Taiwan.
Teng-Hung YuDivision of Cardiology, Department of Internal Medicine, E-Da Hospital, Kaohsiung, Taiwan.
Chia-Chang HsuDivision of Gastroenterology and Hepatology, Department of Internal Medicine, E-Da Hospital, Kaohsiung, Taiwan.
Ya-Ai ChengDepartment of Health Care Administration, College of Medicine, I-Shou University, Kaohsiung, Taiwan.
Fu-Mei ChungDivision of Cardiology, Department of Internal Medicine, E-Da Hospital, Kaohsiung, Taiwan.
Yau-Jiunn LeeLee's Endocrinologic Clinic, Pingtung, Taiwan.
Yung-Chuan LuSchool of Medicine for International Students, College of Medicine, I-Shou University, Kaohsiung, Taiwan.
E-Da Hospital · TWI-Shou University · TWPingtung Hospital · TWTaipei Veterans General Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A urine albumin/creatinine ratio (UACR) <30 mg/g is considered to be normal, while increased risk of incident hypertension and cardiovascular disease mortality in subjects with high normal UACR level had been observed. However, a mild elevated but normal UACR level was associated with the risk of initiating chronic kidney disease (CKD) is uncertain. We investigated whether higher normal UACR is associated with the risk of developing CKD. A total of 4821 subjects with type 2 diabetes mellitus (T2DM), an estimated glomerular filtration rate >60 ml/min/1.73 m

Indexed as

Diabetes Mellitus, Type 2Renal Insufficiency, ChronicAlbuminsAlbuminuriaCreatinineFemaleHumansMaleAlbuminsCreatininechronic kidney diseaselow-grade albuminuriaprogressionriskType 2 diabetes mellitus

Identifiers

PMID35721762
PMCPMC9200995
OpenAlexW4281802675

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.