Evidence map›Paper›PMID 35721703›Full record

SynthesisFrontiers in endocrinology2022

Association of Diabetes Mellitus With Postoperative Complications and Mortality After Non-Cardiac Surgery: A Meta-Analysis and Systematic Review.

Xiaoying Zhang, Aisheng Hou, Jiangbei Cao, Yanhong Liu, Jingsheng Lou, Hao Li, Yulong Ma, Yuxiang Song, Weidong Mi, Jing Liu

Open access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Frontiers in endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
68citing papers in PubMed, 3 pooled it
11.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

68 citing papers in PubMed, 3 syntheses or guidelines pooled it, 83 citations in OpenAlex.

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8 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Xiaoying ZhangDepartment of Anesthesiology, The First Medical Center of Chinese PLA General Hospital, Beijing, China.
Aisheng HouDepartment of Anesthesiology, The First Medical Center of Chinese PLA General Hospital, Beijing, China.
Jiangbei CaoDepartment of Anesthesiology, The First Medical Center of Chinese PLA General Hospital, Beijing, China.
Yanhong LiuDepartment of Anesthesiology, The First Medical Center of Chinese PLA General Hospital, Beijing, China.
Jingsheng LouDepartment of Anesthesiology, The First Medical Center of Chinese PLA General Hospital, Beijing, China.
Hao LiDepartment of Anesthesiology, The First Medical Center of Chinese PLA General Hospital, Beijing, China.
Yulong MaDepartment of Anesthesiology, The First Medical Center of Chinese PLA General Hospital, Beijing, China.
Yuxiang SongDepartment of Anesthesiology, The First Medical Center of Chinese PLA General Hospital, Beijing, China.
Weidong MiDepartment of Anesthesiology, The First Medical Center of Chinese PLA General Hospital, Beijing, China.
Jing LiuDepartment of Anesthesiology, The First Medical Center of Chinese PLA General Hospital, Beijing, China.
Chinese PLA General Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Although a variety of data showing that diabetes mellitus (DM) (Type 1 or Type 2) is associated with postoperative complication, there is still a lack of detailed studies that go through the specific diabetic subgroups. The goal of this meta-analysis is to assess the relationship between DM and various complications after non-cardiac surgery. Methods: We searched articles published in three mainstream electronic databases (PubMed, EMBASE, Web of science) before November, 2020. A random effects model was conducted since heterogeneity always exist when comparing results between different types of surgery. Results: This paper included 125 studies with a total sample size of 3,208,776 participants. DM was a risk factor for any postoperative complication (Odds ratio (OR)=1.653 [1.487, 1.839]). The risk of insulin-dependent DM (OR=1.895 [1.331, 2.698]) was higher than that of non-insulin-dependent DM (OR=1.554 [1.061, 2.277]) for any postoperative complication. DM had a higher risk of infections (OR=1.537 [1.322, 1.787]), wound healing disorders (OR=2.010 [1.326, 3.046]), hematoma (OR=1.369 [1.120, 1.673]), renal insufficiency (OR=1.987 [1.311, 3.013]), myocardial infarction (OR=1.372 [0.574, 3.278]). Meanwhile, DM was a risk factor for postoperative reoperation (OR=1.568 [1.124, 2.188]), readmission (OR=1.404 [1.274, 1.548]) and death (OR=1.606 [1.178, 2.191]). Conclusions: DM is a risk factor for any postoperative complications, hospitalization and death after non-cardiac surgery. These findings underscore the importance of preoperative risk factor assessment of DM for the safe outcome of surgical patients.

Indexed as

Diabetes Mellitus, Type 1Diabetes Mellitus, Type 2HumansOdds RatioPostoperative ComplicationsRisk Factorsdiabetes mellitusmeta-analysisnon-cardiac surgerypostoperative complicationrisk factor

Identifiers

PMID35721703
PMCPMC9204286
OpenAlexW4281875963

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.