Evidence map›Paper›PMID 35721662›Full record

ArticleAmerican heart journal plus : cardiology research and practice2022

Artificial intelligence opportunities in cardio-oncology: Overview with spotlight on electrocardiography.

Daniel Sierra-Lara Martinez, Peter A Noseworthy, Oguz Akbilgic, Joerg Herrmann, Kathryn J Ruddy, Abdulaziz Hamid, Ragasnehith Maddula, Ashima Singh, Robert Davis, Fatma Gunturkun and 2 more

Open access · goldAbstract read
In one paragraph

Article in American heart journal plus : cardiology research and practice, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
8.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 55 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. Review
  9. Revolutionising Cardio-Oncology Care with Precision Genomics.International journal of molecular sciences · 2025
    Review
  10. Review
  11. Review
  12. Review
  13. Artificial intelligence: Applications in cardio-oncology and potential impact on racial disparities.American heart journal plus : cardiology research and practice · 2024
    Article
  14. Review
  15. Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 2 countries.

Daniel Sierra-Lara MartinezCoronary Care Unit, National Institute of Cardiology/Instituto Nacional de Cardiologia, Ciudad de Mexico, Mexico.
Peter A NoseworthyDepartment of Cardiovascular Diseases, Mayo Clinic, Rochester, MN, USA.
Oguz AkbilgicDepartment of Health Informatics and Data Science, Parkinson School of Health Sciences and Public Health, Loyola University Chicago, Maywood, IL, USA.
Joerg HerrmannDepartment of Cardiovascular Diseases, Mayo Clinic, Rochester, MN, USA.
Kathryn J RuddyDepartment of Oncology, Mayo Clinic, Rochester, MN, USA.
Abdulaziz HamidMedical College of Wisconsin, Milwaukee, WI, USA.
Ragasnehith MaddulaMedical College of Wisconsin, Milwaukee, WI, USA.
Ashima SinghInstitute of Health and Equity, Medical College of Wisconsin, Milwaukee, WI, USA.
Robert DavisCenter for Biomedical Informatics, University of Tennessee Health Sciences Center, USA.
Fatma GunturkunCenter for Biomedical Informatics, University of Tennessee Health Sciences Center, USA.
John L JefferiesDivision of Cardiovascular Diseases, University of Tennessee Health Sciences Center, USA.
Sherry-Ann BrownDepartment of Cardiovascular Diseases, Mayo Clinic, Rochester, MN, USA.
Mayo Clinic in Arizona · USMedical College of Wisconsin · USUniversity of Tennessee Health Science Center · USInstituto Nacional de Cardiología · MXSt. Jude Children's Research Hospital · USWake Forest University · US

Funding

Clinical and Translational Science AwardUL1TR001436 · NCATS · MEDICAL COLLEGE OF WISCONSIN · PI FREED, JULIE K · 2015 to 2025
$47.5M
TrAstuzumab Cardiomyopathy Therapeutic Intervention with Carvedilol (TACTIC) TrialR01CA233610 · NCI · MAYO CLINIC ROCHESTER · PI HERRMANN, JOERG, RUDDY, KATHRYN JEAN · 2019 to 2024
$4.3M
Institutional Career Development CoreKL2TR001438 · NCATS · MEDICAL COLLEGE OF WISCONSIN · PI WIDLANSKY, MICHAEL E · 2015 to 2024
$2.9M
NCATS NIH HHS KL2 TR001438NCATS NIH HHS UL1 TR001436NCI NIH HHS R01 CA233610
6 · The paper itself

Abstract

Cardiovascular disease is a leading cause of death among cancer survivors, second only to cancer recurrence or development of new tumors. Cardio-oncology has therefore emerged as a relatively new specialty focused on prevention and management of cardiovascular consequences of cancer therapies. Yet challenges remain regarding precision and accuracy with predicting individuals at highest risk for cardiotoxicity. Barriers such as access to care also limit screening and early diagnosis to improve prognosis. Thus, developing innovative approaches for prediction and early detection of cardiovascular illness in this population is critical. In this review, we provide an overview of the present state of machine learning applications in cardio-oncology. We begin by outlining some factors that should be considered while utilizing machine learning algorithms. We then examine research in which machine learning has been applied to improve prediction of cardiac dysfunction in cancer survivors. We also highlight the use of artificial intelligence (AI) in conjunction with electrocardiogram (ECG) to predict cardiac malfunction and also atrial fibrillation (AF), and we discuss the potential role of wearables. Additionally, the article summarizes future prospects and critical takeaways for the application of machine learning in cardio-oncology. This study is the first in a series on artificial intelligence in cardio-oncology, and complements our manuscript on echocardiography and other forms of imaging relevant to cancer survivors cared for in cardiology clinical practice.

Indexed as

Artificial intelligenceCancerCardiomyopathyCardio-oncologyElectrocardiographyMalignancyPrecisionPrevention

Identifiers

PMID35721662
PMCPMC9202996
OpenAlexW4226312420

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.