ArticleThe Pan African medical journal2022
[Consanguineous marriages and their effects on non-communicable diseases in the Moroccan population: a cross-sectional study].
Article in The Pan African medical journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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2 citing papers in PubMed, 2 citations in OpenAlex.
- Autoimmune manifestations in children with inborn errors of immunity in Morocco: A study from the national registry.Journal of translational autoimmunity · 2025Article
- Influence of Consanguinity on Non-communicable Diseases in Settat, Morocco: Exploring Susceptibility to Chronic and Complex Health Conditions.Journal of research in health sciences · 2025Article
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Authors and funding
5 authors at 1 institution in 1 country.
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Abstract
Introduction: inbreeding is recognized in many studies as an important factor impacting health across several generations. It poses a real public health problem. The purpose of this study is to determine the effects of inbreeding on non-communicable diseases, in particular susceptibility to a range of chronic and complex diseases in the Moroccan population. Methods: we conducted an analytical cross-sectional study based on a survey conducted in two Moroccan communes: BNI hlal and Foum jemaa. The sample studied consisted of 222 individuals. Odds ratios (ORs) with 95% confidence intervals were calculated for the probability of having the disease by the inbreeding status. The chi-square test was used to assess the relationship between the categorical variables. A p. value < 0.05 was considered significant. Results: a frequency of consanguineous marriages of 43.2% was recorded among respondents vs 41% among their parents. We found that inbreeding between parents increased the chances of consanguineous marriages among offsprings (p = 0.01). The generation of consanguineous parents had a higher risk of developing non-communicable diseases such as cancers, diabetes, cardiovascular diseases, chronic respiratory diseases and chronic renal failure. Conclusion: this study shows an increase in the prevalence of non-communicable diseases in the consanguineous population. This can confirm the influence of genetic factors upon the entire spectrum of the disease and not just inmendelian disorders.
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