Evidence map›Paper›PMID 35721618›Full record

ArticleKidney3602022

Clinical Events and Renal Function in the First Year Predict Long-Term Kidney Transplant Survival.

Jesse D Schold, Robert J Nordyke, Zheng Wu, Frank Corvino, Weiying Wang, Sumit Mohan

Open access · diamondAbstract read
In one paragraph

Article in Kidney360, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
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  5. Efficacy and Safety of Low-Dose ATG Plus Basiliximab Induction in Deceased Donor Kidney Transplantation.Transplant international : official journal of the European Society for Organ Transplantation · 2025
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  13. Comparison of Kidney Graft Function and Survival in an Emulated Trial With Living Donors and Brain-Dead Donors.Transplant international : official journal of the European Society for Organ Transplantation · 2024
    Article
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  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Jesse D ScholdDepartment of Quantitative Health Sciences, Cleveland Clinic, Cleveland, Ohio.ORCID 0000-0002-5341-7286
Robert J NordykeBeta6 Consulting Group, Los Angeles, California.ORCID 0000-0003-2424-7852
Zheng WuGenesis Research, Hoboken, New Jersey.
Frank CorvinoGenesis Research, Hoboken, New Jersey.
Weiying WangGenesis Research, Hoboken, New Jersey.
Sumit MohanDepartment of Medicine, Division of Nephrology, Vagelos College of Physicians and Surgeons and Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York.ORCID 0000-0002-5305-9685
Columbia University · USCleveland Clinic · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Estimated glomerular filtration rate (eGFR) at 1 year post transplantation has been shown to be a strong predictor of long-term graft survival. However, intercurrent events (ICEs) may affect the relationship between eGFR and failure risk. Methods: The OPTN and USRDS databases on single-organ kidney transplant recipients from 2012 to 2016 were linked. Competing risk regressions estimated adjusted subhazard ratios (SHRs) of 12-month eGFR on long-term graft failure, considering all-cause mortality as the competing risk, for deceased donor (DD) and living donor (LD) recipients. Additional predictors included recipient, donor, and transplant characteristics. ICEs examined were acute rejection, cardiovascular events, and infections. Results: Cohorts comprised 25,131 DD recipients and 7471 LD recipients. SHRs for graft failure increased rapidly as 12-month eGFR values decreased from the reference 60 ml/min per 1.73 m Conclusions: Twelve-month eGFR is a strong predictor of long-term graft failure after accounting for clinical events occurring from discharge to 1 year. These findings may improve patient management and clinical evaluation of novel interventions.

Indexed as

Cardiovascular DiseasesKidney TransplantationGlomerular Filtration RateGraft SurvivalHumansKidneyLiving Donorsacute rejectioncardiovascular diseaseepidemiology and outcomesglomerular filtration ratekidney transplantationtransplantationtransplant outcomes

Identifiers

PMID35721618
PMCPMC9136886
OpenAlexW4210427775

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.