Evidence map›Paper›PMID 35721553›Full record

ArticleFrontiers in physiology2022

Tracking Early Systolic Motion for Assessing Acute Response to Cardiac Resynchronization Therapy in Real Time.

Manuel Villegas-Martinez, Magnus Reinsfelt Krogh, Øyvind S Andersen, Ole Jakob Sletten, Ali Wajdan, Hans Henrik Odland, Ole Jakob Elle, Espen W Remme

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Pulse arrival time variation as a non-invasive marker of acute response to cardiac resynchronization therapy.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Manuel Villegas-MartinezThe Intervention Centre, Oslo University Hospital, Oslo, Norway.
Magnus Reinsfelt KroghThe Intervention Centre, Oslo University Hospital, Oslo, Norway.
Øyvind S AndersenInstitute for Surgical Research, Oslo University Hospital, Oslo, Norway.
Ole Jakob SlettenInstitute of Clinical Medicine, University of Oslo, Oslo, Norway.
Ali WajdanThe Intervention Centre, Oslo University Hospital, Oslo, Norway.
Hans Henrik OdlandDepartment of Cardiology and Pediatric Cardiology, Oslo University Hospital, Oslo, Norway.
Ole Jakob ElleThe Intervention Centre, Oslo University Hospital, Oslo, Norway.
Espen W RemmeThe Intervention Centre, Oslo University Hospital, Oslo, Norway.
Oslo University Hospital · NOUniversity of Oslo · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An abnormal systolic motion is frequently observed in patients with left bundle branch block (LBBB), and it has been proposed as a predictor of response to cardiac resynchronization therapy (CRT). Our goal was to investigate if this motion can be monitored with miniaturized sensors feasible for clinical use to identify response to CRT in real time. Motion sensors were attached to the septum and the left ventricular (LV) lateral wall of eighteen anesthetized dogs. Recordings were performed during baseline, after induction of LBBB, and during biventricular pacing. The abnormal contraction pattern in LBBB was quantified by the septal flash index (SFI) equal to the early systolic shortening of the LV septal-to-lateral wall diameter divided by the maximum shortening achieved during ejection. In baseline, with normal electrical activation, there was limited early-systolic shortening and SFI was low (9 ± 8%). After induction of LBBB, this shortening and the SFI significantly increased (88 ± 34%,

Indexed as

cardiac resynchonization therapydyssynchronous wall motionheart failureleft bundle branch block (LBBB)response prediction

Identifiers

PMID35721553
PMCPMC9201723
OpenAlexW4281747635

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.