ArticleComputational toxicology (Amsterdam, Netherlands)2021
Open access · greenAbstract read
In one paragraph
Article in Computational toxicology (Amsterdam, Netherlands), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
4.4field-weighted citation impact, top 4% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 41 citations in OpenAlex.
- Evaluating Pharmacokinetics and Toxicity of Potential Therapeutics Against Enterococcus faecalis in Endodontic Pathologies.Medical science monitor : international medical journal of experimental and clinical research · 2026Article
- Assessing the sensitisation hazard of microbial pesticides: potential value of New Approach Methodologies (NAMs) to overcome current challenges.Archives of toxicology · 2025Review
- Chemosensory tobacco product toxicology part 2: toxicological testing, assays, and state of the science.Toxicological sciences : an official journal of the Society of Toxicology · 2025Review
- Rapid Screening of Anticoagulation Compounds for Biological Target-Associated Adverse Effects Using a Deep-Learning Framework in the Management of Atrial Fibrillation.Bioengineering (Basel, Switzerland) · 2025Article
- Acute and sub-acute toxicity assessment of methanolic stem bark extract of Khaya anthotheca (Meliaceae) in Wistar rats.Tropical medicine and health · 2025Article
- Acute and subacute toxicity of the aqueous extract of Cissus Polyantha Glig and Bradt (Vitaceae) on biochemical and hematological parameters in Wistar rats.BMC complementary medicine and therapies · 2025Article
- A Review of the Most Frequent Compounds, Metals, and Compound and Metal Mixtures Found at U.S. Superfund Sites and Their Carcinogenic Potential.Chemical research in toxicology · 2025Review
- Article
- Evaluation of antiobesogenic properties of fermented foods: In silico insights.Journal of food science · 2025Review
- Embracing sex-specific differences in engineered kidney models for enhanced biological understanding of kidney function.Biology of sex differences · 2024Review
- Article
- Insights into Drug Cardiotoxicity from Biological and Chemical Data: The First Public Classifiers for FDA Drug-Induced Cardiotoxicity Rank.Journal of chemical information and modeling · 2024Article
- Developing a pragmatic consensus procedure supporting the ICH S1B(R1) weight of evidence carcinogenicity assessment.Frontiers in toxicology · 2024Article
- Currently Used Methods to Evaluate the Efficacy of Therapeutic Drugs and Kidney Safety.Biomolecules · 2023Review
- Insights into Drug Cardiotoxicity from Biological and Chemical Data: The First Public Classifiers for FDA DICTrank.bioRxiv : the preprint server for biology · 2023Article
- ProfhEX: AI-based platform for small molecules liability profiling.Journal of cheminformatics · 2023Article
- Antibacterial and Cytotoxic Effects of Biosynthesized Zinc Oxide and Titanium Dioxide Nanoparticles.Microorganisms · 2023Article
- Alternative Methods as Tools for Obesity Research: In Vitro and In Silico Approaches.Life (Basel, Switzerland) · 2022Review
- Principles and Procedures for Assessment of Acute Toxicity IncorporatingComputational toxicology (Amsterdam, Netherlands) · 2022Article
- Current status and future directions for a neurotoxicity hazard assessment framework that integratesComputational toxicology (Amsterdam, Netherlands) · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
27 authors at 12 institutions in 5 countries.
Arianna BassanInnovatune srl, Via Giulio Zanon 130/D, 35129 Padova, Italy.
Vinicius M AlvesThe National Institute of Environmental Health Sciences, Division of the National Toxicology Program, Research Triangle Park, NC 27709, United States.
Alexander AmbergSanofi, R&D Preclinical Safety Frankfurt, Industriepark Hoechst, D-65926 Frankfurt am Main, Germany.
Lennart T AngerGenentech, Inc., 1 DNA Way, South San Francisco, CA 94080, United States.
Lisa BeilkeToxicology Solutions Inc., San Diego, CA, United States.
Andreas BenderAI and Data Analytics, Clinical Pharmacology and Safety Sciences, R&D, AstraZeneca, Cambridge, UK.
Autumn BernalToxCreative, LLC, Laguna Hills, CA, United States.
Mark T D CroninSchool of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, Liverpool, L3 3AF, UK.
Jui-Hua HsiehThe National Institute of Environmental Health Sciences, Division of the National Toxicology Program, Research Triangle Park, NC 27709, United States.
Candice JohnsonInstem, 1393 Dublin Road, Columbus, OH 43215, United States.
Raymond KemperNuvalent, One Broadway, 14th floor, Cambridge, MA 02142, United States.
Moiz MumtazAgency for Toxic Substances and Disease Registry, US Department of Health and Human Services, Atlanta, GA, United States.
Louise NeilsonBroughton Nicotine Services, Oak Tree House, West Craven Drive, Earby, Lancashire BB18 6JZ UK.
Manuela PavanInnovatune srl, Via Giulio Zanon 130/D, 35129 Padova, Italy.
Amy PointonFunctional and Mechanistic Safety, Clinical Pharmacology and Safety Sciences, R&D, AstraZeneca, Cambridge, UK.
Julia PletzSchool of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, Liverpool, L3 3AF, UK.
Patricia RuizAgency for Toxic Substances and Disease Registry, US Department of Health and Human Services, Atlanta, GA, United States.
Daniel P RussoThe Rutgers Center for Computational and Integrative Biology, Camden, NJ 08102, United States.
Yogesh SabnisUCB Biopharma SRL, Chemin du Foriest, B-1420 Braine-l'Alleud, Belgium.
Reena SandhuSafeDose Ltd., 20 Dundas Street West, Suite 921, Toronto, Ontario M5G2H1, Canada.
Markus SchaeferSanofi, R&D Preclinical Safety Frankfurt, Industriepark Hoechst, D-65926 Frankfurt am Main, Germany.
Lidiya StavitskayaUS Food and Drug Administration, Center for Drug Evaluation and Research, Silver Spring, MD 20993, USA.
David T SzaboPPG Industries, Pittsburgh, PA 15146, United States.
Jean-Pierre ValentinUCB Biopharma SRL, Chemin du Foriest, B-1420 Braine-l'Alleud, Belgium.
David WoolleyForthTox Limited, PO Box 13550, Linlithgow, EH49 7YU, UK.
Craig ZwicklTransendix LLC, 1407 Moores Manor, Indianapolis, IN 46229, United States.
Glenn J MyattInstem, 1393 Dublin Road, Columbus, OH 43215, United States.
Agency for Toxic Substances and Disease Registry · USAstraZeneca (United Kingdom) · GBInnova (Italy) · ITLiverpool John Moores University · GBNational Institute of Environmental Health Sciences · USSanofi (Germany) · DEUCB Pharma (Belgium) · BEIndianapolis Zoo · USNational One Call (United Kingdom) · GBPPG Industries (United States) · USRutgers, The State University of New Jersey · USUnited States Food and Drug Administration · US
Funding
Rapid response toxicology prediction platformR44ES026909 · NIEHS · LEADSCOPE, INC. · PI MYATT, GLENN JOHN · 2018 to 2019
$1000kNIEHS NIH HHS R44 ES026909
Abstract
The kidneys, heart and lungs are vital organ systems evaluated as part of acute or chronic toxicity assessments. New methodologies are being developed to predict these adverse effects based on
Indexed as
Computational toxicologyExpert alertsHazard identificationHeartIn SilicoIn Silico toxicology protocolsKidneyLungOrgan toxicityQSARRead-acrossRisk assessment
Identifiers
What OpenQuestion holds
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Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.