Evidence map›Paper›PMID 35721173›Full record

ArticleFrontiers in pharmacology2022

Myeloid Angiotensin II Type 1 Receptor Mediates Macrophage Polarization and Promotes Vascular Injury in DOCA/Salt Hypertensive Mice.

Xue-Feng Yang, Huan Wang, Yue Huang, Jian-Hua Huang, Hao-Lin Ren, Qian Xu, Xiao-Min Su, Ai-Mei Wang, Fu Ren, Ming-Sheng Zhou

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.0field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
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  6. Targeting Macrophages: Therapeutic Approaches in Diabetic Kidney Disease.International journal of molecular sciences · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Xue-Feng YangDepartment of Physiology, Jinzhou Medical University, Jinzhou, China.
Huan WangDepartment of Physiology, Shenyang Medical College, Shenyang, China.
Yue HuangThe First Affiliated Hospital, Jinzhou Medical University, Jinzhou, China.
Jian-Hua HuangThe First Affiliated Hospital, Jinzhou Medical University, Jinzhou, China.
Hao-Lin RenRadiology Department of the First Affiliated Hospital, Dalian Medical University, Dalian, China.
Qian XuDepartment of Physiology, Shenyang Medical College, Shenyang, China.
Xiao-Min SuDepartment of Physiology, Shenyang Medical College, Shenyang, China.
Ai-Mei WangDepartment of Physiology, Jinzhou Medical University, Jinzhou, China.
Fu RenDepartment of Anatomy, Shenyang Medical College, Shenyang, China.
Ming-Sheng ZhouDepartment of Physiology, Shenyang Medical College, Shenyang, China.
Shenyang Medical College · CNJinzhou Medical University · CNDalian Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Activation of the renin-angiotensin system has been implicated in hypertension. Angiotensin (Ang) II is a potent proinflammatory mediator. The present study investigated the role of myeloid angiotensin type 1 receptor (AT1R) in control of macrophage phenotype

Indexed as

Ang II type 1 receptorendothelial dysfunctionmacrophage phenotypesalt-sensitive hypertensionvascular injury

Identifiers

PMID35721173
PMCPMC9204513
OpenAlexW4281748684

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.