Evidence map›Paper›PMID 35721169›Full record

ReviewFrontiers in pharmacology2022

Structural Advances in Voltage-Gated Sodium Channels.

Daohua Jiang, Jiangtao Zhang, Zhanyi Xia

Registry-linked trialAbstract readReview
In one paragraph

Review in Frontiers in pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07757061 (Efficacy of Yìqì Jiànpí Decoction Combined With Plant Lactobacillus in Treating Slow Transit Constipation), which is not on this map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07757061 nacompletednot on this mapstarted 2025, after this paper: background citation

Efficacy of Yìqì Jiànpí Decoction Combined With Plant Lactobacillus in Treating Slow Transit Constipation: A Randomized Controlled Trial

TypeinterventionalSponsorFirst People's Hospital Of Lin'an District, HangzhouRan2025 to 2026Enrolled120ConditionsConstipation, Slow Transit ConstipationArmsYQD (Yìqì Jiànpí Decoction), Plant-derived Lactobacillus, Mosapride Citrate
3 · Its place in the literature

Who cites it

31 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Ligand-based pharmacophore modeling for the discovery of NaJournal of computer-aided molecular design · 2026
    Article
  5. Article
  6. Targeting NaInternational journal of molecular sciences · 2026
    Review
  7. Review
  8. Article
  9. The Chemistry and Biology of the Tetrodotoxin Natural Product Family.Angewandte Chemie (International ed. in English) · 2025
    Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Review
  16. Article
  17. Unplugging lateral fenestrations of NALCN reveals a hidden drug binding site within the pore region.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Daohua JiangLaboratory of Soft Matter Physics, Institute of Physics, Chinese Academy of Sciences, Beijing, China.
Jiangtao ZhangLaboratory of Soft Matter Physics, Institute of Physics, Chinese Academy of Sciences, Beijing, China.
Zhanyi XiaLaboratory of Soft Matter Physics, Institute of Physics, Chinese Academy of Sciences, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Voltage-gated sodium (Na

Indexed as

cryo-EMdrug modulation mechanismgating mechanismpharmocologyvoltage-gated sodium channel

Identifiers

PMID35721169
PMCPMC9204039

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.