Evidence map›Paper›PMID 35721062›Full record

ArticleFrontiers in medicine2022

A Prospective Study to Evaluate the Impact of Golimumab Therapy on Work Productivity and Activity, and Quality of Life in Patients With Rheumatoid Arthritis, Psoriasis Arthritis and Axial Spondyloarthritis in a Real Life Setting in AUSTRIA. The GO-ACTIVE Study.

Christian Dejaco, Thomas Mueller, Omid Zamani, Ulrike Kurtz, Stefan Egger, Johannes Resch-Passini, Anna Totzauer, Babak Yazdani-Biuki, Thomas Schwingenschloegl, Peter Peichl and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
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  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Christian DejacoDepartment of Rheumatology, Medical University of Graz, Graz, Austria.
Thomas MuellerPrivate Office, Graz, Austria.
Omid ZamaniRheuma Zentrum Favoriten, Vienna, Austria.
Ulrike KurtzRheuma Praxis Dr. Kurtz, Gleisdorf, Austria.
Stefan EggerOrdination Gesundheitsquadrat, Vienna, Austria.
Johannes Resch-PassiniRheuma-Zentrum Wien-Oberlaa GmbH, Vienna, Austria.
Anna TotzauerPrivate Office Dr. Anna Totzauer, Gmünd, Austria.
Babak Yazdani-BiukiDr. Schrenk & Dr. Yazdani-Biuki OG - Gruppenpraxis, Fürstenfeld, Austria.
Thomas SchwingenschloeglPrivate Office Dr. Thomas Schwingenschloegl, Wiener Neudorf, Austria.
Peter PeichlPrivate Office Prim. Univ. Doz. Dr. Peter Peichl, Vienna, Austria.
Angelika KrausPrivate Office Dr. Angelika Kraus, Melk, Austria.
Gerhard W NaerrMSD Ges.m.b.H., The Icon Vienna, Vienna, Austria.
Gesundheit Österreich · ATINiTS (Austria) · ATMedical University of Graz · ATMSD (Austria) · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To analyze real-world evidence on work productivity and daily activity impairment (WPAI) and health-related quality of life (HRQoL) in rheumatoid arthritis (RA), psoriatic arthritis (PsA), and axial spondyloarthritis (axSpA) patients treated with golimumab in Austria. Methods: This was a prospective, non-interventional, multi-center study conducted in RA, PsA and axSpA patients initiating golimumab between April 2016 and May 2020 in 40 centers in Austria. WPAI, HRQoL (RAQoL, ankylosing spondylitis (AS)QoL and PsAQoL) questionnaires and disease activity (Clinical Disease Activity Index, CDAI, in RA and PsA; Bath Ankylosing Spondylitis Disease Activity Index, BASDAI, in axSpA) were assessed at baseline and months 3, 6, 12, 18, and 24. Association between WPAI and disease activity was tested using linear regression. Results: We enrolled 233 patients (RA, Conclusions: This real-world study confirms the benefit of golimumab on work productivity/daily activity impairment in Austrian RA, PsA, and axSpA patients.

Indexed as

ankylosing spondylitisbiologicalsgolimumabhealth economicpsoriatic arthritisrheumatoid arthritissocio economicTNF inhibitor

Identifiers

PMID35721062
PMCPMC9201205
OpenAlexW4281640457

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.