Evidence map›Paper›PMID 35721042›Full record

ArticleMedicine and pharmacy reports2022

Progressive disseminated histoplasmosis in idiopathic CD4 lymphocytopenia an underdiagnosed combination - a case report.

Prakrati Yadav, Deepak Kumar, Gopal Krishna Bohra, Mahendra Kumar Garg, Jyotsna N Bharti, Abhishek Hl Purohit, Durga Shankar Meena

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Medicine and pharmacy reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. A Rare Case of Coccidioidomycosis Meningitis.Journal of medical cases · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Prakrati YadavDepartment of Internal Medicine, All India Institute of Medical Sciences, Jodhpur, India.
Deepak KumarDepartment of Internal Medicine, All India Institute of Medical Sciences, Jodhpur, India.
Gopal Krishna BohraDepartment of Internal Medicine, All India Institute of Medical Sciences, Jodhpur, India.
Mahendra Kumar GargDepartment of Internal Medicine, All India Institute of Medical Sciences, Jodhpur, India.
Jyotsna N BhartiDepartment of Pathology, All India Institute of Medical Sciences, Jodhpur, India.
Abhishek Hl PurohitDepartment of Pathology, All India Institute of Medical Sciences, Jodhpur, India.
Durga Shankar MeenaDepartment of Internal Medicine, All India Institute of Medical Sciences, Jodhpur, India.
All India Institute of Medical Sciences Jodhpur · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Progressive disseminated histoplasmosis (PDH) usually presents as fever, anemia, leukopenia, hepatosplenomegaly, lymphadenopathy and pulmonary symptoms. There are few reports on the association of idiopathic CD4 lymphocytopenia (ICL) with histoplasmosis. We describe a 65-year-old female presented with a history of fever, papulo-nodular rash and significant weight loss and diagnosed as progressive disseminated histoplasmosis. All immunocompromised conditions were ruled out. In addition, her 2 consecutive CD4 counts were below 300. The patient was diagnosed with PDH associated with ICL. The patient showed significant improvement with liposomal amphotericin B and itraconazole. Absolute CD4 counts should be done in all cases of progressive disseminated histoplasmosis even in HIV negative individuals to rule out associated ICL.

Indexed as

HIV negative individualsidiopathic CD4 lymphocytopeniaimmunocompromised individualsprogressive disseminated histoplasmosis

Identifiers

PMID35721042
PMCPMC9176308
OpenAlexW3203016238

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.