Evidence map›Paper›PMID 35721014›Full record

ArticleFrontiers in aging neuroscience2022

Cerebellar Continuous Theta Burst Stimulation for Aphasia Rehabilitation: Study Protocol for a Randomized Controlled Trial.

Kai Zheng, Mingyun Chen, Ying Shen, Xinlei Xu, Fanglan Gao, Guilan Huang, Yingying Ji, Bin Su, Da Song, Hui Fang and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in aging neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 3 pooled it
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 3 syntheses or guidelines pooled it, 12 citations in OpenAlex.

  1. Pooled it
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  6. An update on the effects of cerebellar transcranial magnetic stimulation on cognitive function.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Kai ZhengDepartment of Rehabilitation Medicine, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Mingyun ChenDepartment of Rehabilitation Medicine, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Ying ShenRehabilitation Medicine Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Xinlei XuDepartment of Neurorehabilitation, Wuxi Tongren Rehabilitation Hospital, Wuxi, China.
Fanglan GaoDepartment of Neurorehabilitation, Wuxi Tongren Rehabilitation Hospital, Wuxi, China.
Guilan HuangDepartment of Neurorehabilitation, Wuxi Tongren Rehabilitation Hospital, Wuxi, China.
Yingying JiDepartment of Neurorehabilitation, Wuxi Tongren Rehabilitation Hospital, Wuxi, China.
Bin SuDepartment of Neurorehabilitation, Wuxi Tongren Rehabilitation Hospital, Wuxi, China.
Da SongDepartment of Neurorehabilitation, Wuxi Tongren Rehabilitation Hospital, Wuxi, China.
Hui FangDepartment of Neurorehabilitation, Wuxi Tongren Rehabilitation Hospital, Wuxi, China.
Peng LiuDepartment of Rehabilitation Medicine, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Caili RenDepartment of Neurorehabilitation, Wuxi Tongren Rehabilitation Hospital, Wuxi, China.
Tongren Hospital · CNNanjing Medical University · CNWuxi People's Hospital · CNThe First Affiliated Hospital, Sun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Language recovery is limited in moderate to severe post-stroke aphasia patients. Repetitive transcranial magnetic stimulation (rTMS) has emerged as a promising tool in improving language dysfunctions caused by post-stroke aphasia, but the treatment outcome is as yet mixed. Considerable evidence has demonstrated the essential involvement of the cerebellum in a variety of language functions, suggesting that it may be a potential stimulation target of TMS for the treatment of post-stroke aphasia. Theta burst stimulation (TBS) is a specific pattern of rTMS with shorter stimulation times and better therapeutic effects. The effect of continuous TBS (cTBS) on the cerebellum in patients with aphasia with chronic stroke needs further exploration. Methods: In this randomized, sham-controlled clinical trial, patients ( Discussion: This protocol holds promise that cerebellar cTBS is a potential strategy to improve language functions in chronic post-stroke aphasia. The resting-state fMRI may explore the neural mechanism underlying the aphasia rehabilitation with cerebellar cTBS.

Indexed as

aphasiacerebellumcontinuous theta burst stimulationrandomized controlled trial (RCT)study protocol

Identifiers

PMID35721014
PMCPMC9201405
OpenAlexW4281784426

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.