Evidence map›Paper›PMID 35720984›Full record

ArticleFrontiers in chemistry2022

Minor Tobacco Alkaloids as Biomarkers to Distinguish Combusted Tobacco Use From Electronic Nicotine Delivery Systems Use. Two New Analytical Methods.

Peyton Jacob, Lawrence Chan, Polly Cheung, Kristina Bello, Lisa Yu, Gideon StHelen, Neal L Benowitz

Open access · goldAbstract read
In one paragraph

Article in Frontiers in chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Standardized research electronic cigarette acceptability among adult men and women who smoke combustible cigarettes.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2025
    Trial
  2. Highly Stable Photoluminescent CeFAnalytical chemistry · 2026
    Article
  3. Article
  4. Toxicant and Nicotine Exposure in Pregnant Smokers, Vapers, and Nicotine-Replacement Users: Cross-Sectional Study.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2025
    Article
  5. Article
  6. Urinary anatalline and nicotelline cut-points to distinguish between exclusive and dual use of tobacco products.Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals · 2024
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Peyton JacobClinical Pharmacology Program, Division of Cardiology, Department of Medicine, University of California, San Francisco, San Francisco, CA, United States.
Lawrence ChanClinical Pharmacology Program, Division of Cardiology, Department of Medicine, University of California, San Francisco, San Francisco, CA, United States.
Polly CheungClinical Pharmacology Program, Division of Cardiology, Department of Medicine, University of California, San Francisco, San Francisco, CA, United States.
Kristina BelloClinical Pharmacology Program, Division of Cardiology, Department of Medicine, University of California, San Francisco, San Francisco, CA, United States.
Lisa YuClinical Pharmacology Program, Division of Cardiology, Department of Medicine, University of California, San Francisco, San Francisco, CA, United States.
Gideon StHelenClinical Pharmacology Program, Division of Cardiology, Department of Medicine, University of California, San Francisco, San Francisco, CA, United States.
Neal L BenowitzClinical Pharmacology Program, Division of Cardiology, Department of Medicine, University of California, San Francisco, San Francisco, CA, United States.
University of California, San Francisco · US

Funding

Training and Education p489-500P50CA180890 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GLANTZ, STANTON ARNOLD · 2013 to 2018
$20.5M
PROJECT 5: IMPACT OF CHANGING TOBACCO PRODUCT USE ON HEALTHCARE COSTS FOR GENERAL AND VULNERABLE POPULATIONSU54HL147127 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LING, PAMELA MAY · 2018 to 2022
$20.4M
NCI NIH HHS P50 CA180890NHLBI NIH HHS U54 HL147127
6 · The paper itself

Abstract

Biomarkers for the use of electronic nicotine delivery systems (ENDS) are desirable for studies of the health effects of electronic cigarettes and related devices. However, the aerosols inhaled from these devices do not contain substances that are unique to this class of products,

Indexed as

biomarkers of exposuree-cigarettesliquid chromatography -tandem mass spectrometrytobaccotobacco alkaloids

Identifiers

PMID35720984
PMCPMC9198481
OpenAlexW4281769567

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.