Evidence map›Paper›PMID 35720960›Full record

ArticleIJID regions2022

Clinical presentation of COVID-19 at the time of testing and factors associated with pre-symptomatic cases in Cameroon.

Tejiokem Mathurin Cyrille, Sadeuh-Mba Serge, Tchatchueng Mbougwa Jules Brice, Tagnouokam Ngoupo Paul Alain, Ngondi Grace, Fokam Joseph, Hamadou Achta, Nke Gisèle, Nwobegahay Julius, Tongo Marcel and 8 more

Open access · goldAbstract read
In one paragraph

Article in IJID regions, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 9 institutions in 1 country.

Tejiokem Mathurin CyrilleEpidemiology and Public Health Service, Pasteur Centre in Cameroon, Yaoundé, Cameroon.
Sadeuh-Mba SergeVirology Service, Pasteur Centre in Cameroon, Yaoundé, Cameroon.
Tchatchueng Mbougwa Jules BriceEpidemiology and Public Health Service, Pasteur Centre in Cameroon, Yaoundé, Cameroon.
Tagnouokam Ngoupo Paul AlainVirology Service, Pasteur Centre in Cameroon, Yaoundé, Cameroon.
Ngondi GraceVirology Laboratory, Laquintinie Hospital, Douala, Cameroon.
Fokam JosephChantal BIYA International Reference Centre for research on HIV/AIDS prevention and management, Yaoundé, Cameroon.
Hamadou AchtaEpidemiology and Public Health Service, Pasteur Centre in Cameroon, Yaoundé, Cameroon.
Nke GisèleCentral Hospital of Yaoundé, Cameroon.
Nwobegahay JuliusMilitary Health Research Center, Yaoundé, Cameroon.
Tongo MarcelEmerging and Reemerging Diseases Research Centre, IMPM, Yaoundé, Cameroon.
Sander MelissaTuberculosis Reference Laboratory Bamenda, Bamenda, Cameroon.
Ndip LucyLaboratory of Emerging Infectious Diseases, University of Buea, Buea, Cameroon.
Perraut RonaldPasteur Centre in Cameroon, Annex of Garoua, Garoua, Cameroon.
Okomo Assoumou Marie ClaireNational Public Health Laboratory, Yaoundé, Cameroon.
Pefura Yone Eric WalterJamot Hospital, Yaoundé, Cameroon.
Etoundi Mballa Georges AlainPublic Health Emergency Operations Coordination Centre, Yaoundé, Cameroon.
Njouom RichardVirology Service, Pasteur Centre in Cameroon, Yaoundé, Cameroon.
Eyangoh SaraPublic Health Emergency Operations Coordination Centre, Yaoundé, Cameroon.
Centre Pasteur du Cameroun · CMCentral Hospital of Yaoundé · CMCentre International De Reference Chantal Biya · CMInstitut de Recherches Médicales et d’Etudes des Plantes Médicinales · CMMinistry of Public Health · CMUniversity of Bamenda · CMUniversity of Buea · CMUniversity of Douala · CMYaoundé General Hospital · CM

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: To describe the clinical features at time of testing and explore factors associated with SARS-CoV-2 infection and pre-symptomatic cases in Cameroon. Methods: Data was collected on people in Cameroon who participated in COVID-19 testing by real-time reverse transcriptase-polymerase chain reaction between 1 March and 5 October 2020. After descriptive analysis, multivariate logistic regression was used to identify factors associated with SARS-CoV-2 infection and pre-symptomatic cases. Results: Of 85 206 test participants, 14 863 (17.4%) were infected with SARS-CoV-2. The median age for cases was 38.4 years (interquartile range 29.6-49.4); 6.1% were aged <19 years, and 6.3% were ≥65 years. Of these cases, 46.5% had at least one symptom/sign with a median time from illness onset to testing of 6 days (interquartile range 3-9). Cough (64.2%), headache (46.5%), fatigue/malaise (46.0%), shortness of breath (30.6%) and myalgia/arthralgia (25.6%) were the most commonly observed symptoms/signs. Pre-symptomatic SARS-CoV-2 infection was associated with age <50 years, being male and absence of comorbidities. Conclusion: This study provides a comprehensive summary of the early clinical profile of SARS-CoV-2 infection during the first wave of COVID-19 in Cameroon, which was dominated by pre-symptomatic illness. These findings would be helpful for SARS-CoV-2 surveillance and control at a regional level.

Indexed as

associated factorsCameroonearly clinical featuresFirst wave COVID-19pre-symptomaticSARS-CoV-2 testing

Identifiers

PMID35720960
PMCPMC9148624
OpenAlexW4281959346

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.