ArticleProceedings of SPIE--the International Society for Optical Engineering
CONTINUITY: CONnectivity Tool with INtegration of sUbcortical regions, regIstration and visualization of TractographY.
Elodie Piot, Maria Bagonis, Juan C Prieto, Martin Styner
Abstract read
In one paragraphArticle in Proceedings of SPIE--the International Society for Optical Engineering. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 · Who and what moneyAuthors and funding
4 authors.
Elodie PiotUniversity of North Carolina, Chapel Hill, United States.
Maria BagonisUniversity of North Carolina, Chapel Hill, United States.
Juan C PrietoUniversity of North Carolina, Chapel Hill, United States.
Martin StynerUniversity of North Carolina, Chapel Hill, United States.
Funding
Cellular and molecular mechanisms governing cortical surface area overgrowth in iPSC-derived neural cells from longitudinally characterized individuals with autismR01HD055741 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Joseph Piven · 2007 to 2026
$52.6MUNC MRDD Research CenterP30HD003110 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BELGER, AYSENIL · 1985 to 2012
$28.7MMRI-Based Presymptomatic Prediction of ASD, and Early Infant to School-Age Brain-Behavior Trajectories, Mechanisms, and Related OutcomesR01MH118362 · NIMH · WASHINGTON UNIVERSITY · PI John R Pruett · 2019 to 2026
$16.3MPreclinical CoreP50HD103573 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Mark D Shen · 2020 to 2026
$9.7MPreclinical CoreU54HD079124 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MOY, SHERYL S · 2013 to 2019
$8.0MEarly Brain Development in TwinsR01MH070890 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI GILMORE, JOHN HORACE · 2004 to 2014
$5.3MUNC/UMN Baby Connectome ProjectU01MH110274 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ELISON, JED THOMAS, GILMORE, JOHN HORACE · 2016 to 2019
$4.5MEarly Brain Development in One and Two Year OldsR01HD053000 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI GILMORE, JOHN HORACE · 2007 to 2018
$4.4MParsing early emerging heterogeneity related to autism spectrum disorderR01MH115046 · NIMH · UNIVERSITY OF MINNESOTA · PI ELISON, JED THOMAS, JACOB, SUMA · 2019 to 2023
$3.8MThe Development of Individual Differences in Adolescent Brain Structure and RiskR01MH123747 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI GILMORE, JOHN HORACE · 2021 to 2025
$3.8MThe Origins of Preadolescent Risk for Psychiatric Disorders in Early Childhood Brain DevelopmentR01MH111944 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI GILMORE, JOHN HORACE · 2017 to 2021
$3.5MInfant Brain and Behavioral Signatures of Later Emerging Risk for PsychopathologyR01MH104324 · NIMH · UNIVERSITY OF MINNESOTA · PI ELISON, JED THOMAS · 2014 to 2018
$2.6MNIA NIH HHS R21 AG059065NICHD NIH HHS P30 HD003110NICHD NIH HHS P50 HD103573NICHD NIH HHS R01 HD053000NICHD NIH HHS R01 HD055741NICHD NIH HHS U54 HD079124NIMH NIH HHS R01 MH070890NIMH NIH HHS R01 MH104324NIMH NIH HHS R01 MH111944NIMH NIH HHS R01 MH115046NIMH NIH HHS R01 MH118362NIMH NIH HHS R01 MH123747NIMH NIH HHS T32 MH106440NIMH NIH HHS U01 MH110274
6 · The paper itselfAbstract
In this work, we present CONTINUITY, a novel, open-source interactive computation and visualization tool for brain connectome data. The connectome processing pipeline performs surface based processing as the main mode of operation. The automated processing includes structural-to-diffusion image co-registration, surface reconstruction for subcortical structures, as well as fiber tractography. The tool supports 3 different probabilistic methods of tractography offered by the tractography frameworks in FSL, MRtrix and DIPY. All methods employ brain and subcortical surfaces as seeds to initialize the tractography algorithms. CONTINUITY implements a friendly Graphical User Interface (GUI) to make the workflow accessible for nontechnical users. Additionally, it offers the possibility to visualize the results of the brain connectome in several interactive plot types such as a hierarchical edge bundling circle plot and over 2D/3D brain templates. This visualization tool can also be applied to connectome matrices computed with other tools and pipelines.
Indexed as
brain connectomeConnectivityOpen-source softwareprobabilistic tractographyregistrationsubcortical regions
Identifiers
PMID35720672
PMCPMC9205324
What OpenQuestion holds
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LicenceTDM
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