Evidence map›Paper›PMID 35720479›Full record

ArticleOncology letters2022

BPTF activates the MAPK pathway through coexpression with Raf1 to promote proliferation of T-cell lymphoma.

Dongyu Bai, Yong Zhou, Fayan Shen, Dehong Gao, Wenhao Suo, Haiping Zhang, Heng Li

Open access · diamondAbstract read
In one paragraph

Article in Oncology letters, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 5 citations in OpenAlex.

  1. BPTF is essential for vaccine-induced germinal center B cell responses.Journal of immunology (Baltimore, Md. : 1950) · 2026
    Article
  2. BPTF-665aa mediate chromatin remodeling drives chemoresistance in T-LBL/ALL.Journal of experimental & clinical cancer research : CR · 2025
    Article
  3. Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Dongyu BaiDepartment of Pathology, The First Affiliated Hospital of Xiamen University, Xiamen, Fujian 361003, P.R. China.
Yong ZhouDepartment of Hematology, The First Affiliated Hospital of Xiamen University, Xiamen, Fujian 361003, P.R. China.
Fayan ShenDepartment of Pathology, The First Affiliated Hospital of Xiamen University, Xiamen, Fujian 361003, P.R. China.
Dehong GaoDepartment of Pathology, The First Affiliated Hospital of Xiamen University, Xiamen, Fujian 361003, P.R. China.
Wenhao SuoDepartment of Pathology, The First Affiliated Hospital of Xiamen University, Xiamen, Fujian 361003, P.R. China.
Haiping ZhangDepartment of Pathology, The First Affiliated Hospital of Xiamen University, Xiamen, Fujian 361003, P.R. China.
Heng LiDepartment of Pathology, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang 150000, P.R. China.
First Affiliated Hospital of Xiamen University · CNFirst Affiliated Hospital of Harbin Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of the present study was to explore the role and biological function of bromodomain PHD finger transcription factor (BPTF) in T-cell lymphoma. Reverse transcription-quantitative PCR (RT-qPCR), western blotting, immunohistochemistry and bioinformatics analysis were used to determine the expression levels of BPTF and Raf1 in T-cell lymphoma tissues and matched adjacent normal tissues. RT-qPCR and western blot analyses were used to examine the role of BPTF in the activation of MAPK signaling. The function of BPTF and Raf1 in T-cell lymphoma was investigated through

Indexed as

bromodomain PHD finger transcription factorMAPK pathwayRaf1T-cell lymphoma

Identifiers

PMID35720479
PMCPMC9185150
OpenAlexW4281477792

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.