Evidence map›Paper›PMID 35720383›Full record

ArticleFrontiers in immunology2022

Diurnal Differences in Intracellular Replication Within Splenic Macrophages Correlates With the Outcome of Pneumococcal Infection.

Ryan G Hames, Zydrune Jasiunaite, Giuseppe Ercoli, Joseph J Wanford, David Carreno, Kornelis Straatman, Luisa Martinez-Pomares, Hasan Yesilkaya, Sarah Glenn, E Richard Moxon and 3 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 2 countries.

Ryan G HamesDepartment of Genetics and Genome Biology, University of Leicester, Leicester, United Kingdom.
Zydrune JasiunaiteDepartment of Genetics and Genome Biology, University of Leicester, Leicester, United Kingdom.
Giuseppe ErcoliCentre for Inflammation and Tissue Repair, UCL Respiratory, Division of Medicine, University College Medical School, London, United Kingdom.
Joseph J WanfordDepartment of Genetics and Genome Biology, University of Leicester, Leicester, United Kingdom.
David CarrenoDepartment of Genetics and Genome Biology, University of Leicester, Leicester, United Kingdom.
Kornelis StraatmanAdvanced Imaging Facility, University of Leicester, Leicester, United Kingdom.
Luisa Martinez-PomaresSchool of Life Sciences, University of Nottingham, Nottingham, United Kingdom.
Hasan YesilkayaDepartment of Respiratory Sciences, University of Leicester, Leicester, United Kingdom.
Sarah GlennPreclinical Research Facility, University of Leicester, Leicester, United Kingdom.
E Richard MoxonDepartment of Paediatrics, University of Oxford, Oxford, United Kingdom.
Peter W AndrewDepartment of Respiratory Sciences, University of Leicester, Leicester, United Kingdom.
Charalambos P KyriacouDepartment of Genetics and Genome Biology, University of Leicester, Leicester, United Kingdom.
Marco R OggioniDepartment of Genetics and Genome Biology, University of Leicester, Leicester, United Kingdom.
University of Leicester · GBUniversity College London · GBUniversity of Bologna · ITUniversity of Nottingham · GBUniversity of Oxford · GB

Funding

Biotechnology and Biological Sciences Research Council BB/S507052/1Medical Research Council MR/M003078/1
6 · The paper itself

Abstract

Circadian rhythms affect the progression and severity of bacterial infections including those caused by

Indexed as

Pneumococcal InfectionsSepsisAnimalsMacrophagesMicePhagocytosisStreptococcus pneumoniaecircadian rhythmimage analysisimmunohistochemistrymacrophagemicroscopymousespleenStreptococcus pneumoniae

Identifiers

PMID35720383
PMCPMC9201068
OpenAlexW4281705628

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.