Evidence map›Paper›PMID 35720313›Full record

ArticleFrontiers in immunology2022

A Molecular Analysis of Memory B Cell and Antibody Responses Against

S Jake Gonzales, Kathleen N Clarke, Gayani Batugedara, Rolando Garza, Ashley E Braddom, Raphael A Reyes, Isaac Ssewanyana, Kendra C Garrison, Gregory C Ippolito, Bryan Greenhouse and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. The N-terminal region of malaria vaccine candidatebioRxiv : the preprint server for biology · 2025
    Article
  3. Article
  4. Article
  5. Differences in phenotype between long-lived memory B cells againstbioRxiv : the preprint server for biology · 2024
    Article
  6. Article
  7. Article
  8. Outsmarting Pathogens with Antibody Engineering.Annual review of chemical and biomolecular engineering · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 3 countries.

S Jake GonzalesDepartment of Microbiology, Immunology and Molecular Genetics, Long School of Medicine, The University of Texas Health Science Center at San Antonio, San Antonio, TX, United States.
Kathleen N ClarkeDepartment of Microbiology, Immunology and Molecular Genetics, Long School of Medicine, The University of Texas Health Science Center at San Antonio, San Antonio, TX, United States.
Gayani BatugedaraDepartment of Microbiology, Immunology and Molecular Genetics, Long School of Medicine, The University of Texas Health Science Center at San Antonio, San Antonio, TX, United States.
Rolando GarzaDepartment of Microbiology, Immunology and Molecular Genetics, Long School of Medicine, The University of Texas Health Science Center at San Antonio, San Antonio, TX, United States.
Ashley E BraddomDepartment of Microbiology, Immunology and Molecular Genetics, Long School of Medicine, The University of Texas Health Science Center at San Antonio, San Antonio, TX, United States.
Raphael A ReyesDepartment of Microbiology, Immunology and Molecular Genetics, Long School of Medicine, The University of Texas Health Science Center at San Antonio, San Antonio, TX, United States.
Isaac SsewanyanaInfectious Disease Research Collaboration, Kampala, Uganda.
Kendra C GarrisonDepartment of Chemical Engineering, University of Texas at Austin, Austin, TX, United States.
Gregory C IppolitoDepartment of Molecular Biosciences and Department of Oncology, Dell Medical School, University of Texas at Austin, Austin, TX, United States.
Bryan GreenhouseDepartment of Medicine, University of California San Francisco, San Francisco, CA, United States.
Sebastiaan BolDepartment of Microbiology, Immunology and Molecular Genetics, Long School of Medicine, The University of Texas Health Science Center at San Antonio, San Antonio, TX, United States.
Evelien M BunnikDepartment of Microbiology, Immunology and Molecular Genetics, Long School of Medicine, The University of Texas Health Science Center at San Antonio, San Antonio, TX, United States.
The University of Texas Health Science Center at San Antonio · USThe University of Texas at Austin · USLondon School of Hygiene & Tropical Medicine · GBUniversity of California, San Francisco · US

Funding

TISSUE CULTURE---COREP30CA054174 · NCI · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI Robin Jean Leach · 1991 to 2026
$59.1M
Transmission ProjectU19AI089674 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MATTHEW G DORSEY, MOSES Robert KAMYA · 2010 to 2026
$29.3M
Institute for Integration of Medicine & Science: A Partnership to Improve HealthUL1TR001120 · NCATS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI CLARK, ROBERT A, HARGREAVES, KENNETH M · 2013 to 2017
$16.5M
Defining conserved epitopes on polymorphic malaria antigensR01AI153425 · NIAID · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI BUNNIK, EVELIEN MARGARETHA · 2021 to 2025
$2.7M
NRSA Training Core (TL1)TL1TR002647 · NCATS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI CHUN, YONG-HEE PATRICIA, FREI, CHRISTOPHER R. · 2018 to 2022
$1.8M
Mentoring translational scientists in international infectious disease researchK24AI144048 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Bryan R Greenhouse · 2019 to 2026
$1.6M
Translational Studies of Plasmodium Falciparum Infection DynamicsK23AI076614 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GREENHOUSE, BRYAN R · 2008 to 2012
$609k
High Throughput DNA Sequencer: Illumina HiSeq 3000 SequencerS10OD021805 · OD · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI LAI, ZHAO · 2016 to 2016
$600k
Graduate Research in Immunology Program (GRIP): To train graduate students for successful careers in academia, industry and governmentT32AI138944 · NIAID · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI ZHONG, GUANGMING · 2018 to 2022
$561k
NCATS NIH HHS TL1 TR002647NCATS NIH HHS UL1 TR001120NCI NIH HHS P30 CA054174NIAID NIH HHS K23 AI076614NIAID NIH HHS K24 AI144048NIAID NIH HHS R01 AI153425NIAID NIH HHS T32 AI138944NIAID NIH HHS U19 AI089674NIH HHS S10 OD021805Wellcome Trust
6 · The paper itself

Abstract

Memory B cells (MBCs) and plasma antibodies against

Indexed as

MalariaMerozoite Surface Protein 1AdultAnimalsAntibodies, ProtozoanAntibody FormationChildHumansImmunoglobulin GImmunoglobulin MMemory B CellsMerozoitesPlasmodium falciparumReceptors, Antigen, B-CellUgandaAntibodies, ProtozoanImmunoglobulin GImmunoglobulin MMerozoite Surface Protein 1Receptors, Antigen, B-Celladaptive immune responseantibodieshumoral immunityIgGIgMmalariamemory B cellssomatic hypermutation

Identifiers

PMID35720313
PMCPMC9201334
OpenAlexW4281701703

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.