Evidence map›Paper›PMID 35720246›Full record

ArticleMedicine and pharmacy reports2022

Evaluation of the acid-neutralizing capacity and other properties of antacids marketed in Morocco.

Mohamed Yafout, Hicham Elhorr, Ibrahim Sbai El Otmani, Youssef Khayati

Abstract read
In one paragraph

Article in Medicine and pharmacy reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mohamed YafoutLaboratory of Drug Sciences, Biomedical Research and Biotechnology, Faculty of Medicine and Pharmacy Casablanca, Hassan II University, Casablanca, Morocco.
Hicham ElhorrLaboratory of Drug Sciences, Biomedical Research and Biotechnology, Faculty of Medicine and Pharmacy Casablanca, Hassan II University, Casablanca, Morocco.
Ibrahim Sbai El OtmaniLaboratory of Drug Sciences, Biomedical Research and Biotechnology, Faculty of Medicine and Pharmacy Casablanca, Hassan II University, Casablanca, Morocco.
Youssef KhayatiLaboratory of Drug Sciences, Biomedical Research and Biotechnology, Faculty of Medicine and Pharmacy Casablanca, Hassan II University, Casablanca, Morocco.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aim: The aim of this study was to evaluate the acid-neutralizing capacity (ANC) and other properties of antacid drugs marketed in Morocco. Methods: Samples of 12 antacids were collected from pharmacies and were subjected to the test described in the US Pharmacopoeia in order to measure their ANC. Other properties such as price and sodium content were also studied. Results: All the tested brands met the minimal requirement of 5 mEq. However, Aluminum hydroxide/Magnesium hydroxide combinations showed a superior acid-neutralizing capacity over other products and oral suspensions showed better results compared to other pharmaceutical forms. Regarding the cost of antacids, Aluminum hydroxide/Magnesium hydroxide combinations and calcium carbonate/magnesium carbonate combinations showed the most favorable ANC/price ratio. Some of the antacids studied contain a high amount of sodium. Conclusion: All the antacids marketed in Morocco meet the USP requirement regarding their ANC. However, the ANC value should be included in the antacids' labels so that both patients and physicians can choose the most appropriate product. The ANC value should be evaluated according to the dose of the active substance instead of the minimum labeled dosage in order to allow a better result interpretation.

Indexed as

acid-neutralization capacityantacidsgastroesophageal refluxpeptic ulcerunited states pharmacopoeia

Identifiers

PMID35720246
PMCPMC9177085

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.