Evidence map›Paper›PMID 35720186›Full record

ArticleOxidative medicine and cellular longevity2022

Patchouli Alcohol Inhibits D-Gal Induced Oxidative Stress and Ameliorates the Quality of Aging Cartilage via Activating the Nrf2/HO-1 Pathway in Mice.

Ming Chen, Haiyan Wen, Siqi Zhou, Xinxin Yan, Haohuan Li

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Patchouli Ethanol ExtractAging medicine (Milton (N.S.W)) · 2025
    Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ming Chen *Department of Orthopedics, Renmin Hospital of Wuhan University, Wuhan 430060, China.
Haiyan Wen *Department of Pharmacy, Renmin Hospital of Wuhan University, Wuhan 430060, China.
Siqi Zhou *Department of Orthopedics, Renmin Hospital of Wuhan University, Wuhan 430060, China.
Xinxin YanDepartment of Orthopedics, Renmin Hospital of Wuhan University, Wuhan 430060, China.ORCID https://orcid.org/0000-0003-2309-8680
Haohuan LiDepartment of Orthopedics, Renmin Hospital of Wuhan University, Wuhan 430060, China.ORCID https://orcid.org/0000-0003-3215-5181
Wuhan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chondrocytes play an essential role in maintaining the structure and function of articular cartilage. Oxidative stress occurred in chondrocytes accelerates cell senescence and death, which contributes to the development of osteoarthritis (OA). Patchouli alcohol (PA), a kind of sesquiterpene in

Indexed as

Cartilage, ArticularSesquiterpenesAgingAnimalsAntioxidantsChondrocytesKelch-Like ECH-Associated Protein 1MiceMolecular Docking SimulationNF-E2-Related Factor 2Oxidative StressAntioxidantsKelch-Like ECH-Associated Protein 1NF-E2-Related Factor 2patchouli alcoholSesquiterpenes

Identifiers

PMID35720186
PMCPMC9200550
OpenAlexW4281767730

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.