Evidence map›Paper›PMID 35720135›Full record

ArticleIJID regions2022

Seroprevalence of anti-SARS-CoV-2 antibodies in Senegal: a national population-based cross-sectional survey, between October and November 2020.

Cheikh Talla, Cheikh Loucoubar, Jerlie Loko Roka, Mamadou A Barry, Seynabou Ndiaye, Maryam Diarra, Mareme Seye Thiam, Oumar Faye, Moussa Dia, Mamadou Diop and 17 more

Open access · goldAbstract read
In one paragraph

Article in IJID regions, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 3 pooled it
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 3 syntheses or guidelines pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  4. Article
  5. Article
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  8. SARS-CoV-2 seroprevalence in vaccine-naïve participants from the Democratic Republic of Congo, Guinea, Liberia, and Mali.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2024
    Article
  9. Article
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  11. SARS-CoV-2 seroprevalence in pregnant women during the first three COVID-19 waves in The Gambia.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2023
    Article
  12. Article
  13. U.S. CDC support to internationalPLOS global public health · 2022
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors at 3 institutions in 3 countries.

Cheikh TallaEpidemiology, Clinical Research and Data Sciences Department, Institut Pasteur de Dakar, Dakar, Senegal.
Cheikh LoucoubarEpidemiology, Clinical Research and Data Sciences Department, Institut Pasteur de Dakar, Dakar, Senegal.
Jerlie Loko RokaCenters for Disease Control and Prevention (CDC), Atlanta, Georgia, USA.
Mamadou A BarryEpidemiology, Clinical Research and Data Sciences Department, Institut Pasteur de Dakar, Dakar, Senegal.
Seynabou NdiayeEpidemiology, Clinical Research and Data Sciences Department, Institut Pasteur de Dakar, Dakar, Senegal.
Maryam DiarraEpidemiology, Clinical Research and Data Sciences Department, Institut Pasteur de Dakar, Dakar, Senegal.
Mareme Seye ThiamEpidemiology, Clinical Research and Data Sciences Department, Institut Pasteur de Dakar, Dakar, Senegal.
Oumar FayeVirology Department, Institut Pasteur de Dakar, Dakar, Senegal.
Moussa DiaVirology Department, Institut Pasteur de Dakar, Dakar, Senegal.
Mamadou DiopEpidemiology, Clinical Research and Data Sciences Department, Institut Pasteur de Dakar, Dakar, Senegal.
Oumar NdiayeVirology Department, Institut Pasteur de Dakar, Dakar, Senegal.
Adama TallEpidemiology, Clinical Research and Data Sciences Department, Institut Pasteur de Dakar, Dakar, Senegal.
Rokhaya FayeImmunophysiopathology and Infectious Diseases Department, Institut Pasteur de Dakar, Dakar, Senegal.
Adji Astou MbowImmunophysiopathology and Infectious Diseases Department, Institut Pasteur de Dakar, Dakar, Senegal.
Babacar DioufImmunophysiopathology and Infectious Diseases Department, Institut Pasteur de Dakar, Dakar, Senegal.
Jean Pierre DialloPrevention Department, Surveillance Division, Ministry of Health and Social Action, Dakar, Senegal.
Ibrahima Mamby KeitaPrevention Department, Surveillance Division, Ministry of Health and Social Action, Dakar, Senegal.
Mamadou NdiayePrevention Department, Surveillance Division, Ministry of Health and Social Action, Dakar, Senegal.
Tom WoudenbergMalaria: Parasites and Hosts Unit, Department of Parasites and Insect Vectors, Institut Pasteur, Paris, France.
Michael WhiteMalaria: Parasites and Hosts Unit, Department of Parasites and Insect Vectors, Institut Pasteur, Paris, France.
Jim TingCenters for Disease Control and Prevention (CDC), Atlanta, Georgia, USA.
Cheikh Tidiane DiagneVirology Department, Institut Pasteur de Dakar, Dakar, Senegal.
Omer PasiCenters for Disease Control and Prevention (CDC), Atlanta, Georgia, USA.
Boly DiopPrevention Department, Surveillance Division, Ministry of Health and Social Action, Dakar, Senegal.
Amadou A SallVirology Department, Institut Pasteur de Dakar, Dakar, Senegal.
Inès Vigan-WomasImmunophysiopathology and Infectious Diseases Department, Institut Pasteur de Dakar, Dakar, Senegal.
Ousmane FayeVirology Department, Institut Pasteur de Dakar, Dakar, Senegal.
Institut Pasteur de Dakar · SNCenters for Disease Control and Prevention · USInstitut Pasteur · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: A nationwide cross-sectional epidemiological survey was conducted to capture the true extent of coronavirus disease 2019 (COVID-19) exposure in Senegal. Methods: Multi-stage random cluster sampling of households was performed between October and November 2020, at the end of the first wave of COVID-19 transmission. Anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies were screened using three distinct ELISA assays. Adjusted prevalence rates for the survey design were calculated for each test separately, and thereafter combined. Crude and adjusted prevalence rates based on test performance were estimated to assess the seroprevalence. As some samples were collected in high malaria endemic areas, the relationship between SARS-CoV-2 seroreactivity and antimalarial humoral immunity was also investigated. Results: Of the 1463 participants included in this study, 58.8% were female and 41.2% were male; their mean age was 29.2 years (range 0.20-84.8.0 years). The national seroprevalence was estimated at 28.4% (95% confidence interval 26.1-30.8%). There was substantial regional variability. All age groups were impacted, and the prevalence of SARS-CoV-2 was comparable in the symptomatic and asymptomatic groups. An estimated 4 744 392 (95% confidence interval 4 360 164-5 145 327) were potentially infected with SARS-CoV-2 in Senegal, while 16 089 COVID-19 RT-PCR laboratory-confirmed cases were reported by the national surveillance. No correlation was found between SARS-CoV-2 and Conclusions: These results provide a better estimate of SARS-CoV-2 dissemination in the Senegalese population. Preventive and control measures need to be reinforced in the country and especially in the south border regions.

Indexed as

ELISAIgG and IgMPopulation-based surveySARS-CoV-2SenegalSerologySeroprevalence

Identifiers

PMID35720135
PMCPMC8897837
OpenAlexW4220826661

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.