Evidence map›Paper›PMID 35720115›Full record

ArticleFrontiers in molecular biosciences2022

Hierarchical Virtual Screening Based on Rocaglamide Derivatives to Discover New Potential Anti-Skin Cancer Agents.

Igor V F Dos Santos, Rosivaldo S Borges, Guilherme M Silva, Lúcio R de Lima, Ruan S Bastos, Ryan S Ramos, Luciane B Silva, Carlos H T P da Silva, Cleydson B R Dos Santos

Abstract read
In one paragraph

Article in Frontiers in molecular biosciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Igor V F Dos SantosModeling and Computational Chemistry Laboratory, Federal University of Amapá, Macapá, Brazil.
Rosivaldo S BorgesModeling and Computational Chemistry Laboratory, Federal University of Amapá, Macapá, Brazil.
Guilherme M SilvaComputational Laboratory of Pharmaceutical Chemistry, School of Pharmaceutical Sciences of Ribeirão Preto - Universidade de São Paulo, Ribeirão Preto, Brazil.
Lúcio R de LimaModeling and Computational Chemistry Laboratory, Federal University of Amapá, Macapá, Brazil.
Ruan S BastosModeling and Computational Chemistry Laboratory, Federal University of Amapá, Macapá, Brazil.
Ryan S RamosModeling and Computational Chemistry Laboratory, Federal University of Amapá, Macapá, Brazil.
Luciane B SilvaModeling and Computational Chemistry Laboratory, Federal University of Amapá, Macapá, Brazil.
Carlos H T P da SilvaComputational Laboratory of Pharmaceutical Chemistry, School of Pharmaceutical Sciences of Ribeirão Preto - Universidade de São Paulo, Ribeirão Preto, Brazil.
Cleydson B R Dos SantosModeling and Computational Chemistry Laboratory, Federal University of Amapá, Macapá, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Skin Cancer (SC) is among the most common type of cancers worldwide. The search for SC therapeutics using molecular modeling strategies as well as considering natural plant-derived products seems to be a promising strategy. The phytochemical Rocaglamide A (Roc-A) and its derivatives rise as an interesting set of reference compounds due to their

Indexed as

anticancer activityhierarchical virtual screeningpharmacophorerocaglamideskin cancer

Identifiers

PMID35720115
PMCPMC9201829

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.