ArticleApplied sciences (Basel, Switzerland)2021
Dual-Slope Diffuse Reflectance Instrument for Calibration-Free Broadband Spectroscopy.
Article in Applied sciences (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 29 citations in OpenAlex.
- Influence of Uncertainties in Optode Positions on Self-Calibrating or Dual-Slope Diffuse Optical Measurements.Photonics · 2025Article
- Frequency-domain instrument with custom ASIC for dual-slope near-infrared spectroscopy.The Review of scientific instruments · 2024Article
- Cross-wavelength calibrating method for real-time imaging of tissue optical properties using frequency-domain diffuse optical spectroscopy.Biomedical optics express · 2024Article
- Single-distance and dual-slope frequency-domain near-infrared spectroscopy to assess skeletal muscle hemodynamics.Journal of biomedical optics · 2023Article
- Depth-selective method for time-domain diffuse reflectance measurements: validation study of the dual subtraction technique.Biomedical optics express · 2023Article
- Novel data types for frequency-domain diffuse optical spectroscopy and imaging of tissues: characterization of sensitivity and contrast-to-noise ratio for absorption perturbations.Biomedical optics express · 2023Article
- VIS-NIR Diffuse Reflectance Spectroscopy System with Self-Calibrating Fiber-Optic Probe: Study of Perturbation Resistance.Diagnostics (Basel, Switzerland) · 2023Article
- Dual-slope imaging of cerebral hemodynamics with frequency-domain near-infrared spectroscopy.Neurophotonics · 2023Article
- Optical imaging and spectroscopy for the study of the human brain: status report.Neurophotonics · 2022Article
- Broadband diffuse optical spectroscopy of two-layered scattering media containing oxyhemoglobin, deoxyhemoglobin, water, and lipids.Journal of innovative optical health sciences · 2022Article
- Broadband absorption spectroscopy of heterogeneous biological tissue.Applied optics · 2021Article
- Noninvasive Optical Measurements of Dynamic Cerebral Autoregulation by Inducing Oscillatory Cerebral Hemodynamics.Frontiers in neurology · 2021Article
Corrections and comments
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
Abstract
This work presents the design and validation of an instrument for dual-slope broadband diffuse reflectance spectroscopy. This instrument affords calibration-free, continuous-wave measurements of broadband absorbance of optically diffusive media, which may be translated into absolute absorption spectra by adding frequency-domain measurements of scattering at two wavelengths. An experiment on a strongly scattering liquid phantom (milk, water, dyes) confirms the instrument's ability to correctly identify spectral features and measure absolute absorption. This is done by sequentially adding three dyes, each featuring a distinct spectral absorption, to the milk/water phantom. After each dye addition, the absorption spectrum is measured, and it is found to reproduce the spectral features of the added dye. Additionally, the absorption spectrum is compared to the absorption values measured with a commercial frequency-domain instrument at two wavelengths. The measured absorption of the milk/water phantom quantitatively agrees with the known water absorption spectrum (
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