Evidence map›Paper›PMID 35719858›Full record

ArticleEnvironmental science & technology letters2022

Elevated Fecal Mitochondrial DNA from Symptomatic Norovirus Infections Suggests Potential Health Relevance of Human Mitochondrial DNA in Fecal Source Tracking.

Kevin J Zhu, Brittany Suttner, Jackie Knee, Drew Capone, Christine L Moe, Christine E Stauber, Kostas T Konstantinidis, Thomas E Wallach, Amy J Pickering, Joe Brown

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Environmental science & technology letters, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Exploring the Pathogen Profiles of Ancient Feces.bioRxiv : the preprint server for biology · 2025
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  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 2 countries.

Kevin J ZhuSchool of Civil and Environmental Engineering, Georgia Institute of Technology, Atlanta, Georgia 30332, United States.ORCID https://orcid.org/0000-0002-4625-2276
Brittany SuttnerSchool of Civil and Environmental Engineering, Georgia Institute of Technology, Atlanta, Georgia 30332, United States.ORCID https://orcid.org/0000-0001-9004-4354
Jackie KneeDepartment of Disease Control, London School of Hygiene and Tropical Medicine, London WC1E 7HT,United Kingdom.ORCID https://orcid.org/0000-0002-0834-8488
Drew CaponeDepartment of Environmental Sciences and Engineering, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States.ORCID https://orcid.org/0000-0002-2138-6382
Christine L MoeCenter for Global Safe Water, Sanitation, and Hygiene, Rollins School of Public Health, Emory University, Atlanta, Georgia 30322, United States.ORCID https://orcid.org/0000-0003-3628-1783
Christine E StauberDepartment of Population Health Sciences, School of Public Health, Georgia State University, Atlanta, Georgia 30302, United States.ORCID https://orcid.org/0000-0002-2226-0976
Kostas T KonstantinidisSchool of Civil and Environmental Engineering, Georgia Institute of Technology, Atlanta, Georgia 30332, United States.ORCID https://orcid.org/0000-0002-0954-4755
Thomas E WallachDivision of Pediatric Gastroenterology, SUNY Downstate Health Sciences University, Brooklyn, New York 11203, United States.
Amy J PickeringDepartment of Civil and Environmental Engineering, University of California, Berkeley, California 94720, United States.ORCID https://orcid.org/0000-0001-6193-2221
Joe BrownDepartment of Environmental Sciences and Engineering, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States.ORCID https://orcid.org/0000-0002-5200-4148
Georgia Institute of Technology · USUniversity of North Carolina at Chapel Hill · USEmory University · USGeorgia State University · USSUNY Downstate Health Sciences University · USUniversity of California, Berkeley · USUniversity of London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An end goal of fecal source tracking (FST) is to provide information on risk of transmission of waterborne illnesses associated with fecal contamination. Ideally, concentrations of FST markers in ambient waters would reflect exposure risk. Human mtDNA is an FST marker that is exclusively human in origin and may be elevated in feces of individuals experiencing gastrointestinal inflammation. In this study, we examined whether human mtDNA is elevated in fecal samples from individuals with symptomatic norovirus infections using samples from the United States (US), Mozambique, and Bangladesh. We quantified hCYTB484 (human mtDNA) and HF183/BacR287 (human-associated

Identifiers

PMID35719858
PMCPMC9202355
OpenAlexW4280614687

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.