Evidence map›Paper›PMID 35719844›Full record

ReviewNeurophotonics2022

Advances in computer-generated holography for targeted neuronal modulation.

M Hossein Eybposh, Vincent R Curtis, Jose Rodríguez-Romaguera, Nicolas C Pégard

Abstract readReview
In one paragraph

Review in Neurophotonics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Disentangling the Neural Circuits of Arousal and Anxiety-Like Behavior.Current topics in behavioral neurosciences · 2025
    Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

M Hossein EybposhUniversity of North Carolina at Chapel Hill, Department of Applied Physical Sciences, Chapel Hill, North Carolina, United States.ORCID https://orcid.org/0000-0002-3934-1609
Vincent R CurtisUniversity of North Carolina at Chapel Hill, Department of Applied Physical Sciences, Chapel Hill, North Carolina, United States.ORCID https://orcid.org/0000-0003-1953-8460
Jose Rodríguez-RomagueraUniversity of North Carolina, Department of Psychiatry, Chapel Hill, North Carolina, United States.ORCID https://orcid.org/0000-0002-1752-229X
Nicolas C PégardUniversity of North Carolina at Chapel Hill, Department of Applied Physical Sciences, Chapel Hill, North Carolina, United States.ORCID https://orcid.org/0000-0003-2868-7118

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genetically encoded calcium indicators and optogenetics have revolutionized neuroscience by enabling the detection and modulation of neural activity with single-cell precision using light. To fully leverage the immense potential of these techniques, advanced optical instruments that can place a light on custom ensembles of neurons with a high level of spatial and temporal precision are required. Modern light sculpting techniques that have the capacity to shape a beam of light are preferred because they can precisely target multiple neurons simultaneously and modulate the activity of large ensembles of individual neurons at rates that match natural neuronal dynamics. The most versatile approach, computer-generated holography (CGH), relies on a computer-controlled light modulator placed in the path of a coherent laser beam to synthesize custom three-dimensional (3D) illumination patterns and illuminate neural ensembles on demand. Here, we review recent progress in the development and implementation of fast and spatiotemporally precise CGH techniques that sculpt light in 3D to optically interrogate neural circuit functions.

Indexed as

calcium imagingcomputer-generated holographyneural modulationoptogeneticsphotostimulationsculpted light

Identifiers

PMID35719844
PMCPMC9201973

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.