Evidence map›Paper›PMID 35719670›Full record

ArticleFrontiers in public health2022

Breast Cancer Survival in Eastern Region of Ghana.

Paddy Ssentongo, John S Oh, Forster Amponsah-Manu, William Wong, Xavier Candela, Yubraj Acharya, Anna E Ssentongo, Daleela G Dodge

Abstract read
In one paragraph

Article in Frontiers in public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  7. Late-Stage Diagnosis of Breast Cancer in Ghana: Needs for Patient and Public Education.Journal of cancer education : the official journal of the American Association for Cancer Education · 2025
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  9. Anticipated First Contact and Time to Seek Healthcare for Possible Breast Cancer Symptoms: A Cross-Sectional Study in Rural Ghana.Health expectations : an international journal of public participation in health care and health policy · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Paddy SsentongoDepartment of Public Health Sciences, Penn State College of Medicine, Hershey, PA, United States.
John S OhDepartment of Surgery, Penn State Hershey Medical Center, Hershey, PA, United States.
Forster Amponsah-ManuDepartment of Surgery, Eastern Regional Hospital, Koforidua, Ghana.
William WongDepartment of Surgery, Penn State Hershey Medical Center, Hershey, PA, United States.
Xavier CandelaDepartment of Surgery, Penn State Hershey Medical Center, Hershey, PA, United States.
Yubraj AcharyaDepartment of Health Policy and Administration, College of Health and Human Development, The Pennsylvania State University, University Park, PA, United States.
Anna E SsentongoDepartment of Public Health Sciences, Penn State College of Medicine, Hershey, PA, United States.
Daleela G DodgeDepartment of Surgery, Penn State Hershey Medical Center, Hershey, PA, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Five-year overall survival rate of breast cancer in low-income countries (LICs) is significantly lower than in high-resource countries. This study explored clinical and pathological factors influencing mortality in the Eastern region of Ghana. Methods: We performed a retrospective medical chart review for patients undergoing surgery and chemotherapy for breast cancer at a regional hospital in Ghana from January 2014 to January 2017. Descriptive and survival analysis was done. Results: One hundred and twenty-nine patients were included in the study. The median age at presentation was 51 years. Sixty percent of patients presented with poorly differential histological grade III. The most common histological type was invasive ductal carcinoma (83%). Based on stage assessment using only tumor size and lymph node status, 60% presented at stage 3. Only 25% were tested for hormone receptor proteins and HER2 status. Of these, 57% had triple-negative breast cancer (TNBC). The 3-year overall survival rate was only 52%. Conclusion: The cumulative 3-year survival was 52%. Despite success in reducing cancer mortality in northern Africa, survival in sub-Saharan Africa remains poor. A significantly higher percentage of GIII and TNBC is found in breast cancers seen in Ghana. When combined with limited capacity for accurate diagnosis, cancer subtype analysis, adequate therapy, and follow-up, late-stage presentation leads to poor outcomes. Future studies should emphasize the identification of barriers to care and opportunities for cost-effective and sustainable improvements in diagnosing and treating breast cancer in LICs.

Indexed as

Erb-b2 Receptor Tyrosine KinasesTriple Negative Breast NeoplasmsGhanaHumansRetrospective StudiesSurvival RateErb-b2 Receptor Tyrosine KinasesAfricabreast cancerepidemiologyGhanasurvival

Identifiers

PMID35719670
PMCPMC9201058

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.