Evidence map›Paper›PMID 35719363›Full record

ArticleFrontiers in cellular and infection microbiology2022

Intestine-Specific NHE3 Deletion in Adulthood Causes Microbial Dysbiosis.

Jianxiang Xue, Jessica A Dominguez Rieg, Linto Thomas, James R White, Timo Rieg

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
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  9. Review
  10. Effects of Dietary Supplement of ProbioticAquaculture nutrition · 2025
    Article
  11. New functions and roles of the NaPflugers Archiv : European journal of physiology · 2024
    Review
  12. Article
  13. Effect of supplementation withFrontiers in microbiology · 2024
    Article
  14. Article
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Jianxiang XueDepartment of Molecular Pharmacology and Physiology, University of South Florida, Tampa, FL, United States.
Jessica A Dominguez RiegDepartment of Molecular Pharmacology and Physiology, University of South Florida, Tampa, FL, United States.
Linto ThomasDepartment of Molecular Pharmacology and Physiology, University of South Florida, Tampa, FL, United States.
James R WhiteResphera Biosciences LLC, Baltimore, MD, United States.
Timo RiegDepartment of Molecular Pharmacology and Physiology, University of South Florida, Tampa, FL, United States.
James A. Haley Veterans' Hospital · USUniversity of South Florida · USResphera Biosciences · US

Funding

Role of Renal and Intestinal AC6 and NHE3 for Phosphate HomeostasisR01DK110621 · NIDDK · VETERANS MEDICAL RESEARCH FDN/SAN DIEGO · PI RIEG, TIMO · 2016 to 2020
$1.7M
Pharmacological Npt2a inhibition as a treatment for hyperphosphatemia in chronic kidney diseaseI01BX004968 · VA · JAMES A. HALEY VA MEDICAL CENTER · PI RIEG, TIMO · 2021 to 2024
–
BLRD VA I01 BX004968NIDDK NIH HHS R01 DK110621
6 · The paper itself

Abstract

In the intestine, the Na

Indexed as

Gastrointestinal MicrobiomeInflammatory Bowel DiseasesAdultAnimalsBacillotaBacteroidetesDysbiosisHumansIntestinesMiceSodium-Hydrogen Exchanger 3SLC9A3 protein, humanSlc9a3 protein, mouseSodium-Hydrogen Exchanger 3colitisdysbiosisinflammatory bowel diseaseintestinemicrobiomeNHE3ulcerative colitis

Identifiers

PMID35719363
PMCPMC9204535
OpenAlexW4281724005

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.