Evidence map›Paper›PMID 35719175›Full record

ArticleLancet regional health. Americas2022

ACOG and local diagnostic criteria for hypertensive disorders of pregnancy (HDP) in La Paz-El Alto, Bolivia: A retrospective case-control study.

Litzi Lazo-Vega, Lilian Toledo-Jaldin, Abraham Badner, José Luis Barriga-Vera, Melany Castro-Monrroy, Anna G Euser, Alison Larrea-Alvarado, Ian Lawrence, Carola Mérida, Rodrigo Mizutani and 6 more

Open access · goldAbstract read
In one paragraph

Article in Lancet regional health. Americas, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Surviving birth at high altitude.The Journal of physiology · 2024
    Review
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 7 institutions in 2 countries.

Litzi Lazo-VegaHospital Materno-Infantil, Caja Nacional de Salud, La Paz, Bolivia.
Lilian Toledo-JaldinHospital Materno-Infantil, Caja Nacional de Salud, La Paz, Bolivia.
Abraham BadnerHospital Materno-Infantil, Caja Nacional de Salud, La Paz, Bolivia.
José Luis Barriga-VeraHospital Boliviano Holandés, El Alto, Bolivia.
Melany Castro-MonrroyUniversidad Major de San Andrés, Escuela de Medicina, La Paz, Bolivia.
Anna G EuserDepartment of Obstetrics and Gynecology, University of Colorado Denver, Anschutz Medical Campus, MS 8913, 12700 E 19th Avenue, Aurora, CO 80045, USA.
Alison Larrea-AlvaradoHospital Materno-Infantil, Caja Nacional de Salud, La Paz, Bolivia.
Ian LawrenceUniversity of Colorado Denver School of Medicine, Aurora, CO, USA.
Carola MéridaUniversidad Major de San Andrés, Escuela de Medicina, La Paz, Bolivia.
Rodrigo MizutaniHospital Boliviano Holandés, El Alto, Bolivia.
Yuri PérezHospital de la Mujer, La Paz, Bolivia.
Sebastian RocabadoUniversidad Nuestra Señora de La Paz, Escuela de Medicina, La Paz, Bolivia.
Manfredo VargasHospital Boliviano Holandés, El Alto, Bolivia.
Vikram VasanKrieger School of Arts and Sciences, The Johns Hopkins University, Baltimore, MD, USA.
Colleen G JulianDepartment of Medicine, University of Colorado Denver, Aurora, CO, USA.
Lorna G MooreDepartment of Obstetrics and Gynecology, University of Colorado Denver, Anschutz Medical Campus, MS 8913, 12700 E 19th Avenue, Aurora, CO 80045, USA.
Instituto Boliviano de Ciencia y Tecnología Nuclear · BOUniversidad Mayor de San Andrés · BOUniversity of Colorado Anschutz Medical Campus · USUniversity of Colorado Denver · USCentro de Información y Desarrollo de la Mujer · BOJohns Hopkins University · USUniversidad Nuestra Señora de La Paz · BO

Funding

NIH Prior Approval Process ProfessionalUL1TR002535 · NCATS · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2018 to 2022
$51.1M
Effects of chronic hypoxia and AMPK activation on uteroplacental perfusion, placental metabolism and the regulation of fetal growthR01HD088590 · NICHD · UNIVERSITY OF COLORADO DENVER · PI Colleen Glyde Julian, LORNA G. MOORE · 2016 to 2026
$4.3M
Genetic Regulation of Hypoxia-Induced IUGRR01HL079647 · NHLBI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI MOORE, LORNA G. · 2005 to 2008
$1.9M
Epigenetic and Fetal Origins of Hypoxia-Induced Pulmonary HypertensionR01HL138181 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI JULIAN, COLLEEN GLYDE · 2018 to 2021
$1.6M
Antenatal Exposures and Non-Communicable Disease(ANDES): Building research capacity to identify and treat causes of NCD in BoliviaR21TW010797 · FIC · UNIVERSITY OF COLORADO DENVER · PI JULIAN, COLLEEN GLYDE, MOORE, LORNA G. · 2017 to 2018
$389k
FIC NIH HHS R21 TW010797NCATS NIH HHS UL1 TR002535NHLBI NIH HHS R01 HL079647NHLBI NIH HHS R01 HL138181NICHD NIH HHS R01 HD088590
6 · The paper itself

Abstract

Background: Hypertensive disorders of pregnancy (HDP) are a leading cause of maternal death in low- to middle-income countries (LMIC). The American College of Obstetricians and Gynecologists (ACOG) updated diagnostic guidelines to align signs and symptoms with those associated with maternal death. We performed an observational study to ask whether ACOG guidelines were employed and associated with adverse outcomes in La Paz-El Alto, Bolivia, an LMIC. Methods: Medical records for all HDP discharge diagnoses ( Findings: Both systems agreed with respect to eclampsia, but only 27% of all Bolivian HDP diagnoses met ACOG criteria. HDP increased adverse maternal- or perinatal-outcome risks for both systems, but ACOG guidelines enabled more pre-delivery diagnoses, graded maternal-risk assessment, and targeting of HDP terminating in maternal death. Interpretation: Bolivia diagnoses agreed with ACOG guidelines concerning end-stage disease (eclampsia) but not the other HDP due mainly to ACOG's recognition of a broader range of severe features. ACOG guidelines can aid in identifying pregnancies at greatest risk in LMICs, where most maternal and perinatal deaths occur. Funding: NIH TW010797, HD088590, HL138181, UL1 TR002535.

Indexed as

EclampsiaHELLP syndromeHigh altitudeMaternal mortalityPerinatal mortalityPreeclampsia

Identifiers

PMID35719175
PMCPMC9205446
OpenAlexW4229030297

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.