Evidence map›Paper›PMID 35719129›Full record

ArticleFaculty reviews2022

ConducTORs of a Signaling Symphony: Metabolic and Hormone Responses Converge on TOR and EIN2 in plants.

Jacob O Brunkard, Caren Chang, Bruce J Mayer, Christian Meyer, Jen Sheen

Open access · diamondAbstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Faculty reviews, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Jacob O BrunkardUniversity of Wisconsin, Madison.ORCID https://orcid.org/0000-0001-6407-9393
Caren ChangUniversity of Maryland, College Park.ORCID https://orcid.org/0000-0003-0384-5888
Bruce J MayerUniversity of Connecticut School of Medicine.ORCID https://orcid.org/0000-0002-4580-3187
Christian MeyerIJPB, INRAE, Université Paris-Saclay.ORCID https://orcid.org/0000-0002-7994-5693
Jen SheenHarvard Medical School; Massachusetts General Hospital.ORCID https://orcid.org/0000-0001-8970-9267
Harvard University · USUniversity of Connecticut · USUniversity of Maryland, College Park · USUniversity of Wisconsin–Madison · US

Funding

Plant Nutrient-Growth Signaling NetworkR01GM129093 · NIGMS · MASSACHUSETTS GENERAL HOSPITAL · PI SHEEN, JEN · 2018 to 2025
$2.8M
An aminoacyl tRNA synthetase is a nitrogen sensor that activates TOR in plantsDP5OD023072 · OD · UNIVERSITY OF WISCONSIN-MADISON · PI BRUNKARD, JACOB O · 2016 to 2020
$1.6M
NIGMS NIH HHS R01 GM129093NIH HHS DP5 OD023072
6 · The paper itself

Abstract

Development is coordinated by dozens of signals that act in overlapping pathways to orchestrate multicellular growth. Understanding how signaling pathways intersect and diverge at a molecular level is critical to predicting how organisms will react to dynamic environmental conditions. In plants, two antagonistic signaling hubs are strictly required to sense and respond to many nutrients and hormones: TARGET OF RAPAMYCIN (TOR) and ETHYLENE INSENSITIVE 2 (EIN2). In this Landmark report, Fu

Indexed as

EIN2EthyleneplantsTOR

Identifiers

PMID35719129
PMCPMC9190210
OpenAlexW4280502213

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.