Evidence map›Paper›PMID 35718798›Full record

ReviewWorld journal of microbiology & biotechnology2022

A mini-review: mechanism of antimicrobial action and application of surfactin.

Xiaoyu Chen, Yajun Lu, Mengyuan Shan, Hongyuan Zhao, Zhaoxin Lu, Yingjian Lu

Abstract readReview
PubMed Publisher
In one paragraph

Review in World journal of microbiology & biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed.

  1. Exploring RiPP-derivedRSC chemical biology · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Immunomodulatory Properties of the Cyclic Lipopeptide Surfactin.Journal of microbiology and biotechnology · 2026
    Review
  8. Article
  9. Surfactin-ProducingFoods (Basel, Switzerland) · 2026
    Article
  10. Review
  11. Article
  12. Article
  13. Bioprotective Strategies to ControlInternational journal of molecular sciences · 2025
    Review
  14. Article
  15. Article
  16. Article
  17. Identification ofBiomolecules · 2025
    Article
  18. Article
  19. Article
  20. Antimicrobial Activity ofInternational journal of molecular sciences · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xiaoyu ChenCollege of Food Science and Technology, Nanjing Agricultural University, Nanjing, 210095, Jiangsu, China.
Yajun LuCollege of Chemistry and Chemical, Nanjing Tech University, Nanjing, 211816, China.
Mengyuan ShanCollege of Food Science and Technology, Nanjing Agricultural University, Nanjing, 210095, Jiangsu, China.
Hongyuan ZhaoCollege of Food Science and Technology, Nanjing Agricultural University, Nanjing, 210095, Jiangsu, China.
Zhaoxin LuCollege of Food Science and Technology, Nanjing Agricultural University, Nanjing, 210095, Jiangsu, China. fmb@njau.edu.cn.
Yingjian LuCollege of Food Science and Engineering, Nanjing University of Finance and Economics, Nanjing, 210023, Jiangsu, China. yingjianlu@nufe.edu.cn.

Funding

National Natural Science Foundation of China No.32072182
6 · The paper itself

Abstract

Surfactin, an antibacterial lipopeptide produced by different strains of Bacillus subtilis, is a powerful biosurfactant. It also has multiple biological activities including antiviral, anti-mycoplasma and antiprotozoal activities, in addition to the broad-spectrum antimicrobial activities against Gram-positive bacteria, Gram-negative bacteria and fungi. Surfactin may be one of the promising alternatives to antibiotics. Surfactin's chemical structure and physicochemical properties are briefly discussed in this mini-review. Surfactin's antibacterial mechanism is mainly outlined as follows: (1) attacking pathogenic bacteria's cell membrane, causing cell membrane disintegration or osmotic pressure imbalance; (2) inhibiting pathogenic bacteria's protein synthesis, preventing cell reproduction; (3) inhibiting pathogenic bacteria's enzyme activity, affecting normal cell metabolism. This provides basis for the further research and application of surfactin. Finally, the application of surfactin in food and its prospect are summarized in brief.

Indexed as

Bacillus subtilisLipopeptidesAnti-Bacterial AgentsGram-Negative BacteriaPeptides, CyclicAnti-Bacterial AgentsLipopeptidesPeptides, CyclicAntibacterial mechanismApplicationCell membrane damageSurfactin

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.