Evidence map›Paper›PMID 35718794›Full record

Trial reportSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2022

A single-site pilot feasibility randomized trial of a supportive care mobile application intervention for patients with advanced cancer and caregivers.

Alexandra Merz, Amro Mohamed, Cheyenne Corbett, Kris Herring, Jordan Hildenbrand, Susan C Locke, Steven Patierno, Jesse Troy, Steven Wolf, S Yousuf Zafar and 6 more

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03628794 (Pilot Testing the Digital Supportive Care Awareness & Navigation), which is not on this map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03628794 nacompletednot on this map

Pilot Testing the Digital Supportive Care Awareness & Navigation (D-SCAN) Application

TypeinterventionalSponsorDuke UniversityRan2018 to 2019Enrolled60ConditionsSupportive CareArmsD-SCAN
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Effect of applying digital health in palliative care for patients with advanced cancer: a meta-analysis and systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Pooled it
  2. Pooled it
  3. Technology-based applications for relatives and caregivers of people with advanced breast cancer-a scoping review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  4. Review
  5. Article
  6. Development and evaluation of an intelligent individualized nutrition management (iNutrition) applet for postdischarge gastric cancer patients following gastrectomy.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  7. Review
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Alexandra MerzDuke University, Durham, NC, 27710, USA.
Amro MohamedDuke University School of Medicine, Durham, NC, 27710, USA.
Cheyenne CorbettDuke Cancer Institute, Durham, NC, 27710, USA.
Kris HerringDuke Cancer Institute, Durham, NC, 27710, USA.
Jordan HildenbrandDuke University School of Medicine, Durham, NC, 27710, USA.
Susan C LockeDuke Cancer Institute, Durham, NC, 27710, USA.
Steven PatiernoDuke Cancer Institute, Durham, NC, 27710, USA.
Jesse TroyDivision of Biostatistics, Department of Biostatistics and Bioinformatics, Duke University School of Medicine, Durham, NC, 27710, USA.
Steven WolfDivision of Biostatistics, Department of Biostatistics and Bioinformatics, Duke University School of Medicine, Durham, NC, 27710, USA.
S Yousuf ZafarDuke Cancer Institute, Durham, NC, 27710, USA.
Jack ChilcottAstraZeneca, Wilmington, DE, 19803, USA.
Adam HigginsAstraZeneca, Wilmington, DE, 19803, USA.
Hugo ManasseiPublicis Sapient, Cambridge, MA, USA.
Colette McCoyAstraZeneca, Wilmington, DE, 19803, USA.
Trudy L BuckinghamAstraZeneca, Wilmington, DE, 19803, USA.
Thomas W LeBlancDuke Cancer Institute, Durham, NC, 27710, USA. thomas.leblanc@duke.edu.ORCID http://orcid.org/0000-0002-0546-7895

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeMobile health interventions can improve patient care. We developed the Digital Supportive Care Awareness and Navigation (D-SCAN) application (app) to facilitate symptom monitoring and use/awareness of cancer supportive care resources. This study tested feasibility, usability/satisfaction, and preliminary efficacy of D-SCAN.

methodsWe randomized 50 patients with advanced cancer to receive the D-SCAN intervention or usual care; 10 caregivers also received D-SCAN. The primary feasibility outcome was determined by weekly symptom survey completion and end of study procedures. We assessed secondary outcomes including usability/satisfaction, awareness/use of supportive care resources, patient activation, and quality of life via various questionnaires including the Net Promoter Score (NPS), Patient Activation Measure (PAM-13), Functional Assessment of Cancer Therapy-General (FACT-G), and Caregiver Oncology Quality of Life (CarGOQOL) questionnaire.

resultsSeventy-six percent of intervention patients met feasibility criteria, exceeding our pre-determined threshold of 75%. Usability/satisfaction by NPS was high, at 14.3% and 12.5% for patients and caregivers, respectively. Intervention patient and caregiver resource awareness increased by a mean of 3.7 (p = 0.27) and 4.1 items, respectively. Supportive care resource utilization increased by a mean of 0.8 items for intervention patients (p = 0.70) and 0.6 for caregivers. PAM-13 increased by a mean of 1.6 for intervention patients (p = 0.65). FACT-G increased by a mean of 1.1 for intervention patients (p = 0.91), and CarGOQoL increased by a mean of 2.2 (p = 0.41).

conclusionD-SCAN is a feasible, usable, and satisfactory intervention for augmenting patient and caregiver supportive care. Further testing is necessary to formally assess D-SCAN's efficacy and impact on patients and caregivers. CLINICAL TRIAL REGISTRATION NUMBER: NCT03628794. Registered on August 14th, 2018.

Indexed as

Mobile ApplicationsNeoplasmsCaregiversFeasibility StudiesHumansQuality of LifeCancermHealthPatient-reported outcomesSupportive care

Identifiers

PMID35718794

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.