Evidence map›Paper›PMID 35718776›Full record

ArticleBMC veterinary research2022

Perioperative characteristics, histologic diagnosis, complications, and outcomes of dogs undergoing percutaneous drainage, sclerotherapy or surgical management of intrarenal cystic lesions: 18 dogs (2004-2021).

Michail Vagias, Guillaume Chanoit, Loretta J Bubenik-Angapen, Erin A Gibson, Hilde de Rooster, Ameet Singh, Valery F Scharf, Janet A Grimes, Mandy L Wallace, Anne Kummeling and 3 more

Open access · goldAbstract read
In one paragraph

Article in BMC veterinary research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Periapical cysts in dogs: 10 cases (2000-2020).Frontiers in veterinary science · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 11 institutions in 6 countries.

Michail VagiasDepartment of Small Animal Surgery, Section of Small Animal Clinical Studies, University College Dublin, Belfield, Dublin 4, Ireland.
Guillaume ChanoitLangford Vets, University of Bristol, Langford, UK.
Loretta J Bubenik-AngapenSugar Land Veterinary Specialists, 1515 Lake Pointe Parkway, Sugar Land, TX, 77478, USA.
Erin A GibsonDepartment of Surgical and Radiological Science, University of California-Davis School of Veterinary Medicine, Davis, CA, USA.
Hilde de RoosterSmall Animal Department, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium.
Ameet SinghDepartment of Clinical Studies, Ontario Veterinary College, University of Guelph, Guelph, Ontario, Canada.
Valery F ScharfDepartment of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, NC, 27607, USA.
Janet A GrimesDepartment of Small Animal Medicine and Surgery, College of Veterinary Medicine, University of Georgia, Athens, GA, 30602, USA.
Mandy L WallaceDepartment of Small Animal Medicine and Surgery, College of Veterinary Medicine, University of Georgia, Athens, GA, 30602, USA.
Anne KummelingDepartment of Clinical Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands.
James A FlandersDepartment of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY, 14850, USA.
Georgios EvangelouAnimalCare Veterinary Center, 30 D-E, Glyfadas, Strovolos, 2023, Nicosia, Cyprus.
Ronan A MullinsDepartment of Small Animal Surgery, Section of Small Animal Clinical Studies, University College Dublin, Belfield, Dublin 4, Ireland. ronan.mullins@ucd.ie.
University College Dublin · IEUniversity of Georgia · USGhent University · BEHouston Methodist Sugar Land Hospital · USNew York State College of Veterinary Medicine · USNorth Carolina State University · USUnity College · USUniversity of Bristol · GBUniversity of California, Davis · USUniversity of Guelph · CAUtrecht University · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCanine intrarenal cystic lesions (ICLs) are infrequently reported in the veterinary literature. Several treatment options have been described including cyst fenestration (partial nephrectomy/deroofing) +/- omentalization, sclerotherapy using alcohol as a sclerosing agent, percutaneous cyst drainage (PCD), and ureteronephrectomy. Information regarding presenting clinical signs, physical examination findings, histologic diagnosis and outcomes of dogs with ICLs treated by different methods is limited. Medical records of 11 institutions were retrospectively reviewed to identify dogs that underwent PCD, sclerotherapy, surgical deroofing +/- omentalization, or ureteronephrectomy for management of ICLs from 2004 to 2021. Six weeks postoperative/post-procedural follow-up was required. Cases suspected to represent malignancy on preoperative imaging were excluded. The study objective was to provide information regarding perioperative characteristics, complications, and outcomes of dogs undergoing treatment of ICLs.

resultsEighteen dogs were included, with 24 ICLs treated. Ten had bilateral. There were 15 males and 3 females, with crossbreeds predominating. PCD, sclerotherapy, deroofing and ureteronephrectomy were performed in 5 (5 ICLs treated), 7 (11 ICLs), 6 (6), and 7 (7) dogs, respectively, with 5 dogs undergoing > 1 treatment. Seven dogs experienced 8 complications, with requirement for additional intervention commonest. PCD, sclerotherapy and deroofing resulted in ICL resolution in 0/5, 3/11 and 3/6 treated ICLs, respectively. Histopathology identified renal cysts (RCs) in 7/13 dogs with histopathology available and neoplasia in 6/13 (4 malignant, 2 benign). Of 5 dogs diagnosed histopathologically with neoplasia, cytology of cystic fluid failed to identify neoplastic cells. Among 7 dogs with histologically confirmed RCs, 4 had concurrent ICLs in ipsilateral/contralateral kidney, compared with 2/6 dogs with histologically confirmed neoplasia.

conclusionsBenign and neoplastic ICLs were approximately equally common and cystic fluid cytology failed to differentiate the 2. Among renal-sparing treatments, deroofing most commonly resulted in ICL resolution. Presence of concurrent ICLs in ipsilateral/contralateral kidney does not appear reliable in differentiating benign from malignant ICLs.

Indexed as

CystsDog DiseasesAnimalsDogsEthanolFemaleMaleRetrospective StudiesSclerosing SolutionsSclerotherapyEthanolSclerosing SolutionsCyst drainageDeroofingDogIntrarenal cystic lesionRenal cystSclerotherapy

Identifiers

PMID35718776
PMCPMC9208150
OpenAlexW4283171528

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.