ArticleAngewandte Chemie (International ed. in English)2022
The Influence of Strain on the Rotation of an Artificial Molecular Motor.
Article in Angewandte Chemie (International ed. in English), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- A supercharged molecular motor operating by constitutional alteration and proton transfer.Nature chemistry · 2026Article
- Synchronous Rotation Dynamics in a Molecular Motor.Journal of the American Chemical Society · 2026Article
- A Molecular Machine Directs the Synthesis of a Rotaxane.Angewandte Chemie (International ed. in English) · 2026Article
- Directionality Reversal and Shift of Rotational Axis in a Hemithioindigo Macrocyclic Molecular Motor.Journal of the American Chemical Society · 2024Article
- Allosteric control of olefin isomerization kinetics via remote metal binding and its mechanochemical analysis.Nature communications · 2023Article
- A photochemical method to evidence directional molecular motions.Nature communications · 2023Article
- Defining Unidirectional Motions and Structural Reconfiguration in a Macrocyclic Molecular Motor.Journal of the American Chemical Society · 2023Article
- Synchronizing Two Distinct Nano-Circular Sliding Motions in Six-Component Machinery for Double Catalysis.Angewandte Chemie (International ed. in English) · 2022Article
- The Influence of Strain on the Rotation of an Artificial Molecular Motor.Angewandte Chemie (International ed. in English) · 2022Article
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Authors and funding
6 authors.
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No grant is acknowledged in the PubMed record.
Abstract
In artificial small-molecule machines, molecular motors can be used to perform work on coupled systems by applying a mechanical load-such as strain-that allows for energy transduction. Here, we report how ring strain influences the rotation of a rotary molecular motor. Bridging the two halves of the motor with alkyl tethers of varying sizes yields macrocycles that constrain the motor's movement. Increasing the ring size by two methylene increments increases the mobility of the motor stepwise and allows for fine-tuning of strain in the system. Small macrocycles (8-14 methylene units) only undergo a photochemical E/Z isomerization. Larger macrocycles (16-22 methylene units) can perform a full rotational cycle, but thermal helix inversion is strongly dependent on the ring size. This study provides systematic and quantitative insight into the behavior of molecular motors under a mechanical load, paving the way for the development of complex coupled nanomachinery.
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