Evidence map›Paper›PMID 35718667›Full record

Observational studyJournal of geriatric oncology2022

Characterization of older adults with cancer seeking acute emergency department care: A prospective observational study.

Jason J Bischof, Mohamed I Elsaid, John F P Bridges, Ashley E Rosko, Carolyn J Presley, Beau Abar, David Adler, Aveh Bastani, Christopher W Baugh, Steven L Bernstein and 19 more

Open access · greenAbstract readObservational Study
In one paragraph

Observational study in Journal of geriatric oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 5 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

29 authors at 20 institutions in 2 countries.

Jason J BischofDepartments of Emergency Medicine, The Ohio State University Wexner Medical Center, Columbus, OH, USA. Electronic address: jason.bischof@osumc.edu.
Mohamed I ElsaidDepartment of Biomedical Informatics, College of Medicine, The Ohio State University, Columbus, OH, USA. Electronic address: Mohamed.elsaid@osumc.edu.
John F P BridgesDepartment of Biomedical Informatics, College of Medicine, The Ohio State University, Columbus, OH, USA. Electronic address: John.Bridges@osumc.edu.
Ashley E RoskoDepartment of Internal Medicine, Division of Hematology, Ohio State University Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA. Electronic address: Ashley.Rosko@osumc.edu.
Carolyn J PresleyDepartment of Internal Medicine, Division of Medical Oncology, Ohio State University Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA. Electronic address: Carolyn.Presley@osumc.edu.
Beau AbarDepartment of Emergency Medicine, University of Rochester, Rochester, NY, USA. Electronic address: Beau_Abar@URMC.Rochester.edu.
David AdlerDepartment of Emergency Medicine, University of Rochester, Rochester, NY, USA. Electronic address: David_Adler@URMC.Rochester.edu.
Aveh BastaniDepartment of Emergency Medicine, William Beaumont Hospital - Troy Campus, Troy, MI, USA. Electronic address: Aveh.Bastani@beaumont.edu.
Christopher W BaughDepartment of Emergency Medicine, Brigham and Women's Hospital, Boston, MA, USA. Electronic address: cbaugh@bwh.harvard.edu.
Steven L BernsteinDepartment of Emergency Medicine, Yale School of Medicine, New Haven, CT, USA. Electronic address: Steven.L.Bernstein@hitchcock.org.
Christopher J CoyneDepartment of Emergency Medicine, University of California San Diego, San Diego, CA, USA. Electronic address: cjcoyne@ucsd.edu.
Danielle D DurhamDepartment of Radiology, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC, USA. Electronic address: danielle_durham@med.unc.edu.
Corita R GrudzenRonald O. Perelman Department of Emergency Medicine and Population Health, New York University Grossman School of Medicine, New York, NY, USA. Electronic address: Corita.Grudzen@nyulangone.org.
Daniel J HenningDepartment of Emergency Medicine, University of Washington, Seattle, WA, USA. Electronic address: henning2@uw.edu.
Matthew F HudsonPrisma Health Cancer Institute, Greenville, SC, USA. Electronic address: Matt.Hudson@prismahealth.org.
Adam KlotzDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA. Electronic address: klotza@MSKCC.ORG.
Gary H LymanDivision of Public Health Sciences, Fred Hutchinson Cancer Research Center and the Department of Medicine, University of Washington School of Medicine, Seattle, WA, USA. Electronic address: glyman@fredhutch.org.
Troy E MadsenDivision of Emergency Medicine, University of Utah, Salt Lake City, UT, USA. Electronic address: Troy.Madsen@hsc.utah.edu.
Cielito C Reyes-GibbyDepartment of Emergency Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. Electronic address: creyes@mdanderson.org.
Juan Felipe RicoDepartment of Pediatrics, University of South Florida Morsani College of Medicine, Tampa, FL, USA. Electronic address: jrico@health.usf.edu.
Richard J RyanDepartment of Emergency Medicine, University of Cincinnati, Cincinnati, OH, USA. Electronic address: richard.ryan@uc.edu.
Nathan I ShapiroDepartment of Emergency Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA. Electronic address: nshapiro@bidmc.harvard.edu.
Robert SworDepartment of Emergency Medicine, William Beaumont Hospital, Royal Oak, MI, USA. Electronic address: Robert.Swor@beaumont.edu.
Charles R ThomasDepartment of Radiation Oncology, Geisel School of Medicine @ Dartmouth, Lebanon, NH, USA. Electronic address: Charles.R.Thomas@Hitchcock.org.
Arvind VenkatDepartment of Emergency Medicine, Allegheny Health Network, Pittsburgh, PA, USA. Electronic address: Arvind.Venkat@ahn.org.
Jason WilsonDepartment of Emergency Medicine, University of South Florida Morsani College of Medicine, Tampa, FL, USA.
Sai-Ching Jim YeungDepartment of Emergency Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. Electronic address: syeung@mdanderson.org.
Sule YilmazDepartment of Surgery, Division of Supportive Care in Cancer, University of Rochester Medical Center, Rochester, NY, USA. Electronic address: Sule_Yilmaz@URMC.Rochester.edu.
Jeffrey M CaterinoDepartments of Emergency Medicine and Internal Medicine, The Ohio State University Wexner Medical Center, Columbus, OH, USA. Electronic address: Jeffrey.Caterino@osumc.edu.
The Ohio State University · USThe Ohio State University Wexner Medical Center · USThe University of Texas MD Anderson Cancer Center · USUniversity of Rochester · USUniversity of South Florida · USAllegheny Health Network · USBeaumont Hospital, Royal Oak · USBeaumont Hospital, Troy · USBeth Israel Deaconess Medical Center · USBrigham and Women's Hospital · USDartmouth College · USFred Hutch Cancer Center · USMemorial Sloan Kettering Cancer Center · USNew York University · USPrisma Health · USUniversity of California, San Diego · USUniversity of Cincinnati · USUniversity of North Carolina at Chapel Hill · USUniversity of Rochester Medical Center · USUniversity of Utah · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
URCC NCORP Research BaseUG1CA189961 · NCI · UNIVERSITY OF ROCHESTER · PI Michelle C Janelsins, KAREN M. MUSTIAN · 2014 to 2026
$67.7M
Clinical and Translational Cancer Control Research Training ProgramT32CA102618 · NCI · UNIVERSITY OF ROCHESTER · PI Michelle C Janelsins, Gary R Morrow · 2019 to 2026
$2.7M
NCI NIH HHS P30 CA008748NCI NIH HHS UG1 CA189961
6 · The paper itself

Abstract

introductionDisparities in care of older adults in cancer treatment trials and emergency department (ED) use exist. This report provides a baseline description of older adults ≥65 years old who present to the ED with active cancer. MATERIALS AND

methodsPlanned secondary analysis of the Comprehensive Oncologic Emergencies Research Network observational ED cohort study sponsored by the National Cancer Institute. Of 1564 eligible adults with active cancer, 1075 patients were prospectively enrolled, of which 505 were ≥ 65 years old. We recruited this convenience sample from eighteen participating sites across the United States between February 1, 2016 and January 30, 2017.

resultsCompared to cancer patients younger than 65 years of age, older adults were more likely to be transported to the ED by emergency medical services, have a higher Charlson Comorbidity Index score, and be admitted despite no significant difference in acuity as measured by the Emergency Severity Index. Despite the higher admission rate, no significant difference was noted in hospitalization length of stay, 30-day mortality, ED revisit or hospital admission within 30 days after the index visit. Three of the top five ED diagnoses for older adults were symptom-related (fever of other and unknown origin, abdominal and pelvic pain, and pain in throat and chest). Despite this, older adults were less likely to report symptoms and less likely to receive symptomatic treatment for pain and nausea than the younger comparison group. Both younger and older adults reported a higher symptom burden on the patient reported Condensed Memorial Symptom Assessment Scale than to ED providers. When treating suspected infection, no differences were noted in regard to administration of antibiotics in the ED, admissions, or length of stay ≤2 days for those receiving ED antibiotics. DISCUSSION: We identified several differences between older (≥65 years old) and younger adults with active cancer seeking emergency care. Older adults frequently presented for symptom-related diagnoses but received fewer symptomatic interventions in the ED suggesting that important opportunities to improve the care of older adults with cancer in the ED exist.

Indexed as

Emergency Service, HospitalNeoplasmsAgedAnti-Bacterial AgentsCohort StudiesHumansPainProspective StudiesUnited StatesAnti-Bacterial AgentsAcute careEmergency departmentEmergency serviceNeoplasm complicationsneoplasm epidemiologyOlder patients with cancerUnscheduled care

Identifiers

PMID35718667
PMCPMC11137847
OpenAlexW4283076697

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.