Evidence map›Paper›PMID 35718592›Full record

ReviewVaccine2022

Benefit-risk evaluation of COVID-19 vaccination in special population groups of interest.

Paul Moss, Francis Berenbaum, Giuseppe Curigliano, Ayelet Grupper, Thomas Berg, Shanti Pather

Open access · greenAbstract readReview
In one paragraph

Review in Vaccine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 6 institutions in 5 countries.

Paul MossInstitute of Immunology and Immunotherapy, University of Birmingham, Birmingham B15 2TT, UK; Queen Elizabeth Hospital, University Hospitals Birmingham, Birmingham B15 2TH, UK.
Francis BerenbaumSorbonne University, INSERM, AP-HP Saint-Antoine Hospital, Paris, France.
Giuseppe CuriglianoIstituto Europeo di Oncologia, IRCCS, Milan, Italy; Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy.
Ayelet GrupperDepartment of Nephrology, Tel-Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
Thomas BergDivision of Hepatology, Department of Medicine II, Leipzig University Medical Center, 04103 Leipzig, Germany.
Shanti PatherBioNTech SE, Mainz, Germany. Electronic address: shanti.pather@biontech.de.
BioNTech (Germany) · DEInserm · FRLeipzig University · DEQueen Elizabeth Hospital Birmingham · GBTel Aviv University · ILUniversity of Milan · IT

Funding

Medical Research Council MC_PC_20060
6 · The paper itself

Abstract

Several population groups display an increased risk of severe disease and mortality following SARS-CoV-2 infection. These include those who are immunocompromised (IC), have a cancer diagnosis, human immunodeficiency virus (HIV) infection or chronic inflammatory disease including autoimmune disease, primary immunodeficiencies, and those with kidney or liver disease. As such, improved understanding of the course of COVID-19 disease, as well as the efficacy, safety, and benefit-risk profiles of COVID-19 vaccines in these vulnerable groups is paramount in order to inform health policy makers and identify evidence-based vaccination strategies. In this review, we seek to summarize current data, including recommendations by national health authorities, on the impact and benefit-risk profiles of COVID-19 vaccination in these populations. Moving forward, although significant efforts have been made to elucidate and characterize COVID-19 disease course and vaccine responses in these groups, further larger-scale and longer-term evaluation will be instrumental to help further guide management and vaccination strategies, particularly given concerns about waning of vaccine-induced immunity and the recent surge of transmission with SARS-CoV-2 variants of concern.

Indexed as

COVID-19COVID-19 VaccinesVulnerable PopulationsHumansPopulation GroupsSARS-CoV-2VaccinationVaccinesCOVID-19 VaccinesVaccinesCOVID-19ImmunocompromisedKidney diseaseLiver diseaseOncologySpecial populationsVaccination

Identifiers

PMID35718592
PMCPMC9135663
OpenAlexW4281860699

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.