Evidence map›Paper›PMID 35718415›Full record

ReviewHeart failure clinics2022

Radiation-Induced Cardiac Dysfunction: Optimizing Radiation Delivery and Postradiation Care.

Lauren N Pedersen, Menka Khoobchandani, Randall Brenneman, Joshua D Mitchell, Carmen Bergom

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Heart failure clinics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lauren N PedersenDepartment of Radiation Oncology, Washington University School of Medicine, 4921 Parkview Place, St. Louis, MO 63110, USA.
Menka KhoobchandaniDepartment of Radiation Oncology, Washington University School of Medicine, 4921 Parkview Place, St. Louis, MO 63110, USA.
Randall BrennemanDepartment of Radiation Oncology, Washington University School of Medicine, 4921 Parkview Place, St. Louis, MO 63110, USA; Alvin J. Siteman Center, Washington University in St. Louis, St Louis, MO, USA.
Joshua D MitchellCardio-Oncology Center of Excellence, Washington University in St. Louis, St Louis, MO, USA; Alvin J. Siteman Center, Washington University in St. Louis, St Louis, MO, USA; Division of Cardiology, Department of Medicine, Washington University in St. Louis, St Louis, MO, USA.
Carmen BergomDepartment of Radiation Oncology, Washington University School of Medicine, 4921 Parkview Place, St. Louis, MO 63110, USA; Cardio-Oncology Center of Excellence, Washington University in St. Louis, St Louis, MO, USA; Alvin J. Siteman Center, Washington University in St. Louis, St Louis, MO, USA. Electronic address: cbergom@wustl.edu.

Funding

Genetic Modifiers of Radiation Therapy-Induced CardiotoxicityR01HL147884 · NHLBI · WASHINGTON UNIVERSITY · PI BERGOM, CARMEN · 2019 to 2023
$2.3M
NHLBI NIH HHS R01 HL147884
6 · The paper itself

Abstract

Radiation therapy (RT) is part of standard-of-care treatment of many thoracic cancers. More than 60% of patients receiving thoracic RT may eventually develop radiation-induced cardiac dysfunction (RICD) secondary to collateral heart dose. This article reviews factors contributing to a thoracic cancer patient's risk for RICD, including RT dose to the heart and/or cardiac substructures, other anticancer treatments, and a patient's cardiometabolic health. It is also discussed how automated tracking of these factors within electronic medical record environments may aid radiation oncologists and other treating physicians in their ability to prevent, detect, and/or treat RICD in this expanding patient population.

Indexed as

Heart DiseasesRadiotherapy Planning, Computer-AssistedHeartHumansBreast cancerCancerDeep inspiration breath holdElectronic medical recordImplementation scienceLung cancerRadiationRadiation-induced cardiac dysfunction

Identifiers

PMID35718415
PMCPMC13234931

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.