Evidence map›Paper›PMID 35718414›Full record

ReviewHeart failure clinics2022

Cardioprotection of High-Risk Individuals.

Jenica N Upshaw, Sharanya Mohanty, Akash Rastogi

Open access · greenAbstract readReview
In one paragraph

Review in Heart failure clinics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jenica N UpshawDivision of Cardiology, Tufts Medical Center, 800 Washington St, Boston, MA 02111, USA. Electronic address: jupshaw@tuftsmedicalcenter.org.
Sharanya MohantyDivision of Cardiology, Tufts Medical Center, 800 Washington St, Boston, MA 02111, USA.
Akash RastogiDivision of Cardiology, Tufts Medical Center, 800 Washington St, Boston, MA 02111, USA.
Tufts Medical Center · US

Funding

CTSA Graduate ProgramTL1TR002546 · NCATS · TUFTS UNIVERSITY BOSTON · PI KENT, DAVID M · 2018 to 2022
$4.2M
Tufts BIRCWH ProgramK12AR084217 · NIAMS · TUFTS UNIVERSITY BOSTON · PI Karen Freund, Iris Z Jaffe · 2023 to 2026
$2.5M
Prevention of Anthracycline Chemotherapy CardiotoxicityK08HL146959 · NHLBI · TUFTS MEDICAL CENTER · PI UPSHAW, JENICA · 2020 to 2024
$885k
NCATS NIH HHS TL1 TR002546NHLBI NIH HHS K08 HL146959NIAMS NIH HHS K12 AR084217
6 · The paper itself

Abstract

Targeting cardioprotective strategies to patients at the highest risk for cardiac events can help maximize therapeutic benefits. Dexrazoxane, liposomal formulations, continuous infusions, and neurohormonal antagonists may be useful for cardioprotection for anthracycline-treated patients at the highest risk for heart failure. Prevalent cardiovascular disease is a risk factor for cardiac events with many cancer therapies, including anthracyclines, anti-human-epidermal growth factor receptor-2 therapy, radiation, and BCR-Abl tyrosine kinase inhibitors, and may be a risk factor for cardiac events with other therapies. Although evidence for cardioprotective strategies is sparse for nonanthracycline therapies, optimizing cardiac risk factors and prevalent cardiovascular disease may improve outcomes.

Indexed as

Antineoplastic AgentsCardiovascular DiseasesHeart FailureAnthracyclinesHeartHumansRisk FactorsAnthracyclinesAntineoplastic AgentsAnthracyclinesCardio-oncologyCardiovascular diseaseChemotherapyHeart failureRadiation

Identifiers

PMID35718414
PMCPMC10984350
OpenAlexW4283017211

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.